89866

p-Toluenesulfonic acid monohydrate

analytical standard

• Formule linéaire : CH₃C₆H₄SO₃H · H₂O
• Numéro CAS: 6192-52-5
• Poids moléculaire : 190.22
• Numéro Beilstein : 3568023
• Numéro MDL: MFCD00142137
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Densité de vapeur: 5.9 (vs air)
• Pureté: 95.0-105.0% (anhydrous basis, T)
• Forme: solid
• Durée de conservation: limited shelf life, expiry date on the label
• Impuretés: 9.5-11.5% water
• Pf: 103-106 °C (lit.)
• Chaîne SMILES: [H]O[H].Cc1ccc(cc1)S(O)(=O)=O
• InChI: 1S/C7H8O3S.H2O/c1-6-2-4-7(5-3-6)11(8,9)10;/h2-5H,1H3,(H,8,9,10);1H2
• Clé InChI: KJIFKLIQANRMOU-UHFFFAOYSA-N

Description

Application

• p-Toluenesulfonic acid monohydrate in organic synthesis: p-Toluenesulfonic acid monohydrate serves as a powerful catalyst in various organic syntheses, including the synthesis of bioactive molecules. It facilitates a range of reactions such as esterifications and acylations crucial for developing pharmaceutical compounds. The use of this catalyst is integral to enhancing reaction rates and improving yield efficiencies in medicinal chemistry (Kim et al., 2022).


• Pharmaceutical synthesis reagent: As a versatile reagent, p-Toluenesulfonic acid monohydrate is utilized in pharmaceutical research for the synthesis of complex drug molecules. Its role in improving the solubility and stability of pharmaceutical agents underscores its importance in drug development processes, particularly in the formulation of active pharmaceutical ingredients (Huang et al., 2020).


• Antioxidant research compound: Researchers use p-Toluenesulfonic acid monohydrate to study antioxidant properties in various chemical systems. Its application in determining the stability and effectiveness of antioxidants helps in the development of new therapeutic agents that combat oxidative stress and related diseases (Fidan et al., 2018).


• Tosic acid hydrate in biochemistry: In biochemistry, p-Toluenesulfonic acid monohydrate is used to study enzyme catalysis and reaction mechanisms. Its application helps in understanding the biochemical pathways where acid catalysis is crucial, providing insights into enzyme behavior and kinetics in biological systems (Kwiecień et al., 2016).


• Catalysis in pharmaceutical research: p-Toluenesulfonic acid monohydrate is extensively used in catalysis within pharmaceutical research to enhance the efficiency of chemical reactions. This application is critical for the rapid and cost-effective synthesis of new drug candidates, highlighting its pivotal role in accelerating drug discovery and development (Kim et al., 2022).

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 8A - Combustible corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable