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821835

TOYOPEARL GigaCap® S-650M Bulk Media

bottle of 1 L, phase sulphonyl, 75 μm particle size

Synonyme(s) :

TOYOPEARL GigaCap® S-650 Cation Exchange Media

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About This Item

Code UNSPSC :
41115700

Gamme de produits

TOYOPEARL®

Forme

slurry

Caractéristiques

counter ion Na+

Conditionnement

bottle of 1 L

Fabricant/nom de marque

Tosoh 21835

Paramètres

3 bar max. pressure

Technique(s)

LPLC: suitable

Matrice

hydroxylated methacrylic polymer

Groupe de la matrice active

sulphonyl phase

Taille des particules

75 μm

pH de fonctionnement

3-13

Capacité

156 g/L±20 adsorption capacity (hIgG)

Technique de séparation

cation exchange

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Catégories apparentées

Description générale

Toyopearl GigaCap S-650 resin is a high capacity, high resolution cation exchange resin* optimized for process scale applications, including the capture and purification of IgG as well as the polishing of monoclonal antibodies. A Toyopearl HW-65 polymeric bead has been chemically modified to provide a higher number of cationic binding sites for increased resin capacity.
While Toyopearl GigaCap S-650M resin was specifically optimized for IgG, with dynamic binding capacities in the vicinity of 140 mg/mL for IgG, it also exhibits high binding capacities for smaller proteins. Typical dynamic binding capacities for lysozyme are in excess of 160 mg/mL.
Toyopearl GigaCap S-650S resin has dynamic binding capacities approaching 165 g/L for gamma globulin. This high capacity, combined with the 35 μm mean particle size, makes Toyopearl GigaCap S-650S ideal for high resolution applications.
Toyopearl GigaCap S-650 resin is stable at high linear velocities, has good pressure-flow characteristics and will withstand back pressures up to 3 bar. The higher capacity and back pressure stability of Toyopearl GigaCap S-650 resin creates opportunities for increased throughput in downstream cation exchange purification steps.
Toyopearl GigaCap S-650M resin also has excellent base stability in 1.0 mol/L NaOH and shows robust clean in place (CIP) properties with minimal loss of capacity after 50 X 1 hour cycles of caustic exposure also using 1.0 mol/L NaOH. (data)
*specifically designed for packed bed use

Caractéristiques

Clean in place with 0.5 M NaOH or 0.1 M HCl.

Forme physique

72% (v/v) slurry in 20% (v/v) ethanol
Shipped in 20% (v/v) ethanol.

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Informations légales

Toyopearl is a registered trademark of Tosoh Corporation
Toyopearl GigaCap is a registered trademark of Tosoh Corporation

Pictogrammes

Flame
GHS02

Mention d'avertissement

Warning

Mentions de danger

H226

Classification des risques

Flam. Liq. 3

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

104.0 °F - closed cup

Point d'éclair (°C)

40 °C - closed cup

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Lot/Batch Number

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