47775

Menadione (K3)

analytical standard

• Synonyme(s) : Menadione
• Formule empirique (notation de Hill): C₁₁H₈O₂
• Numéro CAS: 58-27-5
• Poids moléculaire : 172.18
• Numéro Beilstein : 1908453
• Numéro CE : 200-372-6
• Numéro MDL: MFCD00001681
• Code UNSPSC : 12164500
• ID de substance PubChem : 24871411

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• CofA (certificat d'analyse): current certificate can be downloaded
• Caractéristiques: standard type fat soluble vitamin
• Conditionnement: ampule of 1000 mg
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Pf: 105-107 °C (lit.)
• Application(s): pharmaceutical (small molecule); vitamins, nutraceuticals, and natural products
• Format: neat
• Température de stockage: 2-30°C
• Chaîne SMILES: CC1=CC(=O)c2ccccc2C1=O
• InChI: 1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
• Clé InChI: MJVAVZPDRWSRRC-UHFFFAOYSA-N
• Informations sur le gène: human ... NQO1(1728)

Description

Description générale

Menadione (K3) is a fat-soluble vitamin precursor and catabolic product of oral phylloquinone (vitamin k1) in the intestine.

Menadione is a prothrombogenic compound and belongs to the Vitamin K class of compounds, which are necessary for the biosynthesis of prothrombin and other blood clotting factors. It is used as a model quinone in cell culture and in vivo investigations. It is obtained as a catabolic product of phylloquinone and circulating precursor of tissue menaquinone-4 in rats.

Application

Menadione (K3) may be used as an analytical reference standard for the quantification of the analyte in biological fluids using liquid chromatography technique.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H302,H315,H317,H319,H335,H410
• Conseils de prudence: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Faceshields, Gloves