U1752

Uridine 5′-monophosphate

≥98%

• Synonyme(s) : U 5′-P, UMP, Uridylic acid
• Formule empirique (notation de Hill): C₉H₁₃N₂O₉P
• Numéro CAS: 58-97-9
• Poids moléculaire : 324.18
• Numéro CE : 200-408-0
• Numéro MDL: MFCD00067346
• Code UNSPSC : 41106305
• ID de substance PubChem : 24900628
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: natural (organic)
• Pureté: ≥98%
• Forme: powder
• Solubilité: H₂O: soluble 50 mg/mL, clear, colorless
• Température de stockage: −20°C
• Chaîne SMILES: OC1C(O)C(OC1COP(O)(O)=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)
• Clé InChI: DJJCXFVJDGTHFX-UHFFFAOYSA-N

Description

Description générale

Uridine 5′-monophosphate acts as a precursor for all pyrimidine nucleotides.

Application

Uridine 5′-monophosphate has been used as a component in isotonic E3 medium for isotonic reconstitution experiments to study its effects on the basal cell response or epithelial cell migration to the wound in the isotonic medium.

Actions biochimiques/physiologiques

Uridine 5′-monophosphate (UMP) is a nucleotide monomer in RNA. It contains the nucleobase uracil along with the ribose sugar and a phosphate group. UMP dietary supplementation enhances neurotransmitter release and neurite outgrowth and also promotes membrane phosphatide production in adult rats. Oral supplementation of DHA, co-administered with UMP, in adult gerbils shows an increase in dendritic spines and neuronal membrane synthesis. It suggests a strategy for the treatment of cognitive disorders resulting from synapse loss.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)