U1006

Uridine 5′-triphosphate trisodium salt solution

HPLC purified, aqueous solution for RNA polymerase transcription

• Synonyme(s) : UTP
• Numéro MDL: MFCD00044310
• Code UNSPSC : 41106305
• ID de substance PubChem : 24900622
• Nomenclature NACRES : NA.52

Propriétés

• Source biologique: yeast (Candida Utilis)
• Pureté: ≥95 (HPLC)
• Forme: liquid
• Concentration: 100 mM in H₂O (adjusted to pH 7 with Trizma^®; base)
• Couleur: colorless
• Activité étrangère: DNase and RNase, none detected
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
• Clé InChI: MMJGIWFJVDOPJF-LLWADOMFSA-K
• Informations sur le gène: human ... P2RY2(5029) ; rat ... P2ry2(29597)

Description

Application

Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca²⁺ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).

Actions biochimiques/physiologiques

UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions.

Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.

Informations légales

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable