SRP3233

RELM-gamma from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

• Synonyme(s) : Resistin-like gamma
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: mouse
• Produit recombinant: expressed in E. coli
• Pureté: ≥98% (HPLC); ≥98% (SDS-PAGE)
• Forme: lyophilized
• Poids mol.: 9.2 kDa
• Conditionnement: pkg of 25 μg
• Technique(s): cell culture | mammalian: suitable
• Impuretés: <0.1 EU/μg endotoxin, tested
• Couleur: white
• Numéro d'accès UniProt: Q8K426
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: mouse ... RETNIG(245195)

Description

Description générale

RELMγ belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The other three known members of this family; Resistin, RELMα, and RELMβ, are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMγ is most closely related to RELMα, but is distinctly secreted to bone marrow, spleen, lung, and in peripheral blood granulocytes. The physiological role of RELMγ may include the promotion or regulation of promyelocytic differentiation, although the specific molecular targets of RELMγ have not been identified. Recombinant murine RELMγ is a 9.2 kDa monomeric protein containing 88 amino acid residues.

Actions biochimiques/physiologiques

RELMγ belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. Recombinant murine RELMg is a 9.2 kDa monomeric protein containing 88 amino acid residues.

Séquence

EGTLESIVEK KVKELLANRD DCPSTVTKTF SCTSITASGR LASCPSGMTV TGCACGYGCG SWDIRDGNTC HCQCSTMDWA TARCCQLA

Forme physique

Lyophilized with no additives.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable