SML1454

Otilonium bromide

≥98% (HPLC)

• Synonyme(s) : N,N-Diethyl-N-methyl-2-[(4-{[2-(octyloxy)benzoyl]amino}benzoyl)oxy]ethanaminium bromide, N,N-Diethyl-N-methyl-2-[[4-[[2-(octyloxy)benzoyl]amino]benzoyl]oxy]-ethanaminium bromide, Octylonium bromide
• Formule empirique (notation de Hill): C₂₉H₄₃BrN₂O₄
• Numéro CAS: 26095-59-0
• Poids moléculaire : 563.57
• Numéro MDL: MFCD00211142
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825892
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: H₂O: 5 mg/mL, clear (warmed)
• Température de stockage: −20°C
• Chaîne SMILES: O=C(NC1=CC=C(C(OCC[N+](CC)(CC)C)=O)C=C1)C2=CC=CC=C2OCCCCCCCC.[Br-]
• InChI: 1S/C29H42N2O4.BrH/c1-5-8-9-10-11-14-22-34-27-16-13-12-15-26(27)28(32)30-25-19-17-24(18-20-25)29(33)35-23-21-31(4,6-2)7-3;/h12-13,15-20H,5-11,14,21-23H2,1-4H3;1H
• Clé InChI: VWZPIJGXYWHBOW-UHFFFAOYSA-N

Description

Description générale

Otilonium bromide is an antispasmodic. It contains a red color ACh (acetylcholine) like moiety bound to an aromatic system that ends with an octyl ether.

Actions biochimiques/physiologiques

Otilonium Bromide is a muscarinic receptor antagonist (antimuscarinic). Otilonium Bromide is a quaternary ammonium salt that exerts spasmolytic action selective on the distal gastrointestinal tract. It is used world-wide for the treatment of irritable bowel syndrome (IBS).

Otilonium bromide has the capability to prevent L-type Ca²⁺ channels and colonic contractile activity. It is a tolerable drug as it is absorbed poorly and has very less side effects.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable