Accéder au contenu
MilliporeSigma
Toutes les photos(1)

Key Documents

View All Documentation

SML0054

Sigma-Aldrich

Schizandrin

≥98% (HPLC)

Synonyme(s) :

(+)-Schizandrin, Schisandrin, Schisandrine, Wuweizi alcohol A, Wuweizichun A

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule empirique (notation de Hill):
C24H32O7
Numéro CAS:
7432-28-2
Poids moléculaire :
432.51
Numéro MDL:
MFCD00905761
Code UNSPSC :
12352200
ID de substance PubChem :
329825121
Nomenclature NACRES :
NA.77

Pureté

≥98% (HPLC)

Forme

powder

Activité optique

[α]/D 75 to 95°, c = 1 in methanol

Couleur

white to beige

Solubilité

DMSO: ≥13 mg/mL

Température de stockage

room temp

Chaîne SMILES 

COc1cc2C[C@H](C)[C@@](C)(O)Cc3cc(OC)c(OC)c(OC)c3-c2c(OC)c1OC

InChI

1S/C24H32O7/c1-13-9-14-10-16(26-3)20(28-5)22(30-7)18(14)19-15(12-24(13,2)25)11-17(27-4)21(29-6)23(19)31-8/h10-11,13,25H,9,12H2,1-8H3/t13-,24-/m0/s1

Clé InChI

YEFOAORQXAOVJQ-RZFZLAGVSA-N

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Application

Schizandrin may be used in oxidative stress-related cell signaling studies.

Actions biochimiques/physiologiques

Schizandrin is a natural product with several biological properties involved with antioxidant and anti-inflammatory activities. It reduces the formation of ROS, inhibits the mitochondrial pathway of the apoptotic process and oxidative stress. Schizandrin has been reported to have hepatoprotective, antitumor, antiviral, and antiamnesic effects, and has neuroprotective activity against glutamate induced neurotoxicity.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 7

1 of 7

Schisantherin B phyproof® Reference Substance

PHL83542

Schisantherin B

MST-312 ≥98% (HPLC)

Sigma-Aldrich

M3949

MST-312

Decursin ≥97% (HPLC)

Sigma-Aldrich

SML0786

Decursin

Baicalin 95%

Sigma-Aldrich

572667

Baicalin

4-Hydroxybenzoic acid ReagentPlus®, ≥99%

Sigma-Aldrich

240141

4-Hydroxybenzoic acid

Honokiol ≥98% (HPLC), powder

Sigma-Aldrich

H4914

Honokiol

Betulinic acid ≥98% (HPLC)

Sigma-Aldrich

B8936

Betulinic acid

Ju-Xian Song et al.
Phytotherapy research : PTR, 25(3), 435-443 (2010-08-27)
Aggregated beta-amyloid (Aβ) and elevated plasma levels of homocysteine have been implicated as critical factors in the pathogenesis of Alzheimer's disease. The neuroprotective effects and possible mechanism of four structurally similar dibenzocyclooctadiene lignans (namely schisandrin, schisantherin A, schisandrin B and
Di Hu et al.
Oxidative medicine and cellular longevity, 2012, 721721-721721 (2012-07-26)
In the present study, we examined the effect of schisandrin (SCH) of Schisandra chinensis on the amyloid-beta(1-42)- (Aβ(1-42)-) induced memory impairment in mice and elucidated the possible antioxidative mechanism. Mice were intracerebroventricular (i.c.v.) injected with the aggregated Aβ(1-42) and then
Meng-Shiou Lee et al.
Molecules (Basel, Switzerland), 18(1), 354-372 (2012-12-29)
Glutamate-induced excitotoxicity has been implicated in a variety of neuronal degenerative disorders. In the present study, we investigated the possible neuroprotective effects of schizandrin against apoptosis of primary cultured rat cortical cells induced by glutamate. Glutamate (10 μM) administered for
Fan-Yu Meng et al.
Organic letters, 13(6), 1502-1505 (2011-02-23)
Schiglautone A (1), a unique 6/7/9-fused tricyclic carbon backbone triterpenoid, was isolated from the stems of Schisandra glaucescens. Its structure was determined on the basis of spectroscopic analysis and single-crystal X-ray crystallography. A hypothetical biosynthetic pathway of 1 was postulated.
Seung-Il Jeong et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(3-4), 1045-1053 (2011-12-06)
High glucose (HG) is the underlying factor contributing to long term complication of diabetes mellitus. Reactive oxygen species (ROS) have been postulated as a unifying mechanism for HG-induced complications. NADPH oxidase, producing superoxide anion, is the main source of ROS
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique