SCP0260
[Ac-Tyr1,D-Phe2]-VIP Antagonist-GRF 1-29
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About This Item
Formule empirique (notation de Hill):
C157H252N44O43S1
Poids moléculaire :
3476.01
Code UNSPSC :
12352209
Nomenclature NACRES :
NA.32
Produits recommandés
Pureté
≥95% (HPLC)
Forme
lyophilized
Composition
Peptide Content, ≥75%
Conditions de stockage
protect from light
Température de stockage
−20°C
Amino Acid Sequence
Ac-Tyr-Phe-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
Application
[Ac-Tyr1,D-Phe2]-GHRF(1-29); [Ac-Tyr1,D-Phe2]-GRF(1-29) is used as an antagonist of vasoactive intestinal peptide (VIP) via its receptor, VPAC.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Kai Yang et al.
Hippocampus, 19(9), 779-789 (2009-01-29)
Vasoactive intestinal peptide (VIP) is a 28-amino acid peptide, which belongs to a superfamily of structurally related peptide hormones including pituitary adenylate cyclase-activating polypeptide (PACAP). Although several studies have identified the involvement of PACAP in learning and memory, little work
D M Liu et al.
The European journal of neuroscience, 12(7), 2243-2251 (2000-08-18)
The effects of vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP27 and PACAP38) on isolated parasympathetic neurons of rat intracardiac and submandibular ganglia were examined under voltage clamp using whole-cell patch-clamp recording techniques. VIP and PACAP (</= 10
Jason Itri et al.
Journal of neurophysiology, 90(3), 1589-1597 (2003-09-11)
Circadian rhythmicity in mammals is generated by a pair of nuclei in the anterior hypothalamus known as the suprachiasmatic nuclei (SCN), whose neurons express a variety of neuropeptides that are thought to play an important role in the circadian timing
J Corbitt et al.
Neuropeptides, 36(1), 34-45 (2002-07-31)
VIP and PACAP38 are closely related peptides that are released in the adrenal gland and sympathetic ganglia and regulate catecholamine synthesis and release. We used PC12 cells as a model system to examine receptor and second messenger pathways by which
Tejashree Redij et al.
Chemical biology & drug design, 99(6), 857-867 (2022-03-22)
We report the discovery of two new 2-aminothiophene based small molecule positive allosteric modulators (PAMs) of glucagon-like peptide 1 receptor (GLP-1R) for the treatment of type 2 diabetes. One of the chemotypes, (S-1), has a molecular weight of 239 g/mol
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