SAB5700187

Anti-APEX1 antibody produced in rabbit

• Synonyme(s) : APE, APE1, APEN, APEX, APEX1, APX, HAP1, REF1
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: 35
• Espèces réactives: human
• Concentration: 6.18 mg/ml
• Technique(s): immunofluorescence: 1:50-1:100; immunoprecipitation (IP): 1:50-1:200; western blot: 1:500-1:2000
• Numéro d'accès UniProt: P27695
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... APEX1(328)

Description

Description générale

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5′ to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.

Immunogène

Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human APEX1 (NP_542380.1).

Forme physique

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Stockage et stabilité

Store at -20℃. Avoid freeze / thaw cycles.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable