SAB4702006

Monoclonal Anti-Cytokeratin 19 FITC produced in mouse

• Synonyme(s) : CK19, CYK19, K19, K1CS, KRT19
• Code UNSPSC : 12352203

Propriétés

• Conjugué: FITC conjugate
• Niveau de qualité: 100
• Type de produit anticorps: primary antibodies
• Clone: A53-B/A2, monoclonal
• Forme: buffered aqueous solution
• Espèces réactives: human
• Concentration: 1 mg/ml
• Technique(s): flow cytometry: suitable
• Isotype: IgG2a
• Numéro d'accès UniProt: P08727
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... KRT19(3880)

Description

Description générale

Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.

Spécificité

The mouse monoclonal antibody A53-B/A2 recognizes the rod domain of cytokeratin 19 (40 kDa), an intracellular antigen constituting intermmediate cytoskeleton filaments. Cytokeratin 19 is not expressed in hepatocytes; it is often co-expressed with cytokeratin 7.

Immunogène

MCF-7 human breast adenocarcinoma cell line

Forme physique

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Notes préparatoires

Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Stockage et stabilité

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Autres remarques

The antibody solution should be gently mixed before use.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable