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Key Documents

SAB4700590

Sigma-Aldrich

Monoclonal Anti-CD62L antibody produced in rat

clone MEL-14, purified immunoglobulin, buffered aqueous solution

Synonyme(s) :

Anti-L-selectin, Anti-Sell

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rat

Conjugué

unconjugated

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

MEL-14, monoclonal

Forme

buffered aqueous solution

Espèces réactives

mouse

Concentration

1 mg/mL

Technique(s)

flow cytometry: suitable

Isotype

IgG2a

Numéro d'accès NCBI

NM_001164059.1

Numéro d'accès UniProt

P18337

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

mouse ... Sell(20343)

Description générale

The rat monoclonal antibody MEL-14 reacts with mouse CD62L (L-selectin), a 75 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.

Immunogène

C3H/eb mouse B cell lymphoma 38C-13

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 0.5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

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Code de la classe de stockage

10 - Combustible liquids

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Heping Xu et al.
Blood, 112(4), 1166-1174 (2008-04-09)
Using noninvasive in vivo imaging and experimental autoimmune uveoretinitis as a model, we show for the first time that the mechanisms controlling blood monocyte recirculation through peripheral and lymphoid tissues alter during inflammation. The recirculation of monocytes in mice with
Robert W Yucha et al.
Tissue engineering. Part A, 20(1-2), 189-196 (2013-08-10)
An estimated 12% of women in the United States suffer from some form of infertility. In vitro fertilization (IVF) is the most common treatment for infertility encompassing over 99% of all assisted reproductive technologies. However, IVF has a low success
Yulia Yu Silaeva et al.
Journal of immunotoxicology, 11(4), 393-399 (2013-12-07)
The concept of immunological surveillance implies that immunogenic variants of tumor cells arising in the organism can be recognized by the immune system. Tumor progression is provided by somatic evolution of tumor cells under the pressure of the immune system.
Alessandro Perrella et al.
Pathogens and disease, 72(2), 124-130 (2014-06-04)
We aimed to verify whether CD4(+)/CD25(+) T cells suppress CD4(+) T cells and secrete Granzyme B (GZB) during acute and chronic hepatitis C (CHC) infection. We enrolled 50 subjects: 20 patients with CHC (Group A), 15 healthy individuals (Group B)
Ira Eickmeier et al.
Journal of hepatology, 60(6), 1143-1150 (2014-02-25)
The enterohepatic circuit of T cells may be responsible for the development of autoimmune liver disease. We employed transgenic mice to characterize phenotype and migration patterns of CD8 T cells activated in liver and gut. We studied the migration of

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