SAB4504126

Anti-phospho-Caspase 3 (pSer¹⁵⁰) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-CASP-3, Anti-Caspase-3
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 31 kDa
• Espèces réactives: mouse, rat, human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P42574
• Numéro d'accès UniProt: P42574
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pSer150)
• Informations sur le gène: human ... CASP3(836)

Description

Description générale

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3 is an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases. CASP3 is mapped to human chromosome 4q35.1.

Immunogène

The antiserum was produced against synthesized peptide derived from human Caspase 3 around the phosphorylation site of Ser150.

Immunogen Range: 116-165

Actions biochimiques/physiologiques

Caspase-3 (CASP3) can degenerate multiple cellular proteins and results in morphological changes and DNA fragmentation in cells at the time of apoptosis. It participates in the growth stimulation. CASP3 plays a major role in the execution phase of apoptosis.

Caractéristiques et avantages

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Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable