SAB4500007

Anti-AKT1 antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : C-AKT/ RAC-PK-β, PKB, Protein kinase Akt-2, Protein kinase B, RAC-PK-α
• Numéro MDL: MFCD01322594
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 55 kDa
• Espèces réactives: mouse, rat, human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P31749
• Numéro d'accès UniProt: P31749
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... AKT1(207)

Description

Description générale

The AKT1 (AKT serine/threonine kinase 1) gene is also called as v-akt murine thymoma viral oncogene homolog 1 and PKBα (protein kinase B). It is upregulated in liver, muscle and adipocytes. AKT1 gene is mapped to human chromosome 14q32. It is a member of AKT family that has an amino-terminal pleckstrin homology (PH) domain, a short α-helical linker and a carboxyl-terminal kinase domain.

Anti-AKT1 Antibody detects endogenous levels of total AKT1 protein.

Immunogène

The antiserum was produced against synthesized peptide derived from human AKT1/2/3.

Immunogen Range: 281-330

Actions biochimiques/physiologiques

The protein encoded by AKT1 (AKT serine/threonine kinase 1) gene controls the survival of cell and anti-apoptotic actions that attack the pathogenesis of several cancers, hence it plays a crucial role in tumorigenesis. In mice, AKT1 is essential for normal development.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable