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Key Documents

SAB4300614

Sigma-Aldrich

Anti-ARNTL antibody produced in rabbit

affinity isolated antibody

Synonyme(s) :

Anti-BMAL1 antibody produced in rabbit, Anti-BMAL1c antibody produced in rabbit, Anti-JAP3 antibody produced in rabbit, Anti-MGC47515 antibody produced in rabbit, Anti-aryl hydrocarbon receptor nuclear translocator-like antibody produced in rabbit

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About This Item

Numéro MDL:
MFCD02262590
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

~69 kDa

Espèces réactives

rat, mouse, human

Concentration

1 mg/mL

Technique(s)

western blot: 1:500-1:1000

Isotype

IgG

Séquence immunogène

(S-S-S-I-L)

Numéro d'accès NCBI

NP_001025443.1

Numéro d'accès UniProt

O00327

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ARNTL(406)

Immunogène

Peptide sequence around aa. 569-573 (S-S-S-I-L), according to the protein ARNTL.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Description de la cible

ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Brian A Hodge et al.
Skeletal muscle, 5, 17-17 (2015-05-23)
Skeletal muscle is a major contributor to whole-body metabolism as it serves as a depot for both glucose and amino acids, and is a highly metabolically active tissue. Within skeletal muscle exists an intrinsic molecular clock mechanism that regulates the
Brian A Hodge et al.
eLife, 8 (2019-02-23)
In the present study we show that the master myogenic regulatory factor, MYOD1, is a positive modulator of molecular clock amplitude and functions with the core clock factors for expression of clock-controlled genes in skeletal muscle. We demonstrate that MYOD1
Michael L Rossetti et al.
American journal of physiology. Endocrinology and metabolism, 317(4), E631-E645 (2019-07-31)
Androgen depletion in humans leads to significant atrophy of the limb muscles. However, the pathways by which androgens regulate limb muscle mass are unclear. Our laboratory previously showed that mitochondrial degradation was related to the induction of autophagy and the

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