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Key Documents

SAB4300383

Sigma-Aldrich

Anti-ICAM1 (Ab-512) antibody produced in rabbit

affinity isolated antibody

Synonyme(s) :

Anti-BB2 antibody produced in rabbit, Anti-CD54 antibody produced in rabbit, Anti-P3.58 antibody produced in rabbit, Anti-intercellular adhesion molecule 1 antibody produced in rabbit

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About This Item

Numéro MDL:
MFCD00240668
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

~92 kDa

Espèces réactives

human

Concentration

1 mg/mL

Technique(s)

western blot: 1:500-1:1000

Isotype

IgG

Séquence immunogène

(K-K-Y-R-L)

Numéro d'accès NCBI

NP_000192.2

Numéro d'accès UniProt

P05362

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ICAM1(3383)

Immunogène

Peptide sequence around aa. 510-514 (K-K-Y-R-L), according to the protein ICAM1.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Description de la cible

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Réf. du produit
Description
Tarif

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Ruofeng Qiu et al.
Journal of biomedical science, 19, 99-99 (2012-11-23)
The effects of atorvastatin on SDF-1α expression under acute myocardial infarction (AMI) are still unclear. Therefore, our present study is to investigate the roles and mechanisms of atorvastatin treatment on SDF-1α expression in rats with AMI. Male Sprague-Dawley rats were
Xiao Ke et al.
Archives of medical science : AMS, 13(4), 956-961 (2017-07-20)
Atorvastatin and sitagliptin are able to exert cardio-protective effects. However, whether atorvastatin plus sitagliptin could confer additive benefits for rats with myocardial infarction (MI) is unknown. Forty rats with MI were produced and 37 surviving rats were randomly divided into
Maddalena Noviello et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 22(7), 1342-1352 (2014-04-17)
Stem cell therapy is a promising approach to regenerate healthy tissues starting from a limited amount of self-renewing cells. Immunological rejection of cell therapy products might represent a major limitation. In this study, we investigated the immunological functional profile of
Gi Soo Youn et al.
Toxicology and applied pharmacology, 280(1), 42-52 (2014-07-30)
HIV-1 Tat causes extensive neuroinflammation that may progress to AIDS-related encephalitis and dementia. Celastrol possesses various biological activities such as anti-oxidant, anti-tumor, and anti-inflammatory activities. In this study, we investigated the modulatory effects of celastrol on HIV-1 Tat-induced inflammatory responses
Serom Lee et al.
Toxicology in vitro : an international journal published in association with BIBRA, 28(8), 1413-1423 (2014-07-16)
To assess the public's propensity for allergic contact dermatitis (ACD), many alternatives to in vivo chemical screening have been developed which generally incorporate a small panel of cell surface and secreted dendritic cell biomarkers. However, given the underlying complexity of
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