SAB4300222

Anti-phospho-EIF2AK2 (pThr⁴⁴⁶) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-EIF2AK1 antibody produced in rabbit, Anti-MGC126524 antibody produced in rabbit, Anti-PKR antibody produced in rabbit, Anti-PRKR antibody produced in rabbit, Anti-eukaryotic translation initiation factor 2-alpha kinase 2 antibody produced in rabbit
• Numéro MDL: MFCD03455796
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: ~74 kDa
• Espèces réactives: human
• Concentration: 1 mg/mL
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotype: IgG
• Séquence immunogène: (K-R-TP-R-S)
• Numéro d'accès NCBI: NP_001129123.1
• Numéro d'accès UniProt: P19525
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pThr446)
• Informations sur le gène: human ... EIF2AK2(5610)

Description

Immunogène

Peptide sequence around phosphorylation site of threonine 446 (K-R-T(p)-R-S), according to the protein EIF2AK2.

Caractéristiques et avantages

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Description de la cible

Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable