SAB4200190

Anti-Sumo-2/3 antibody, Rat monoclonal

clone 3H12, purified from hybridoma cell culture

• Synonyme(s) : Anti-HSMT3, Anti-MGC117191, Anti-SMT3 homolog 2, Anti-SMT3 suppressor of mif two 3 homolog 2, Anti-SMT3B, Anti-SMT3H2, Anti-sentrin 2, Anti-small ubiquitin-like modifier 2, Anti-small ubiquitin-related modifier 2, Anti-ubiquitin-like protein SMT3B, Monoclonal Anti-Sumo-2/3, SUMO-2/3, SUMO2/3
• Numéro MDL: MFCD03455941
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Conjugué: unconjugated
• Forme d'anticorps: purified from hybridoma cell culture
• Type de produit anticorps: primary antibodies
• Clone: 3H12, monoclonal
• Forme: buffered aqueous solution
• Poids mol.: ~11 kDa
• Espèces réactives: mouse, rat, human
• Concentration: ~1.0 mg/mL
• Technique(s): immunocytochemistry: suitable; western blot: 2-4 μg/mL using HeLa cell nuclear extract
• Numéro d'accès UniProt: P55854
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... SUMO3(6612) ; mouse ... Sumo3(20610) ; rat ... Sumo3(499417)

Description

Description générale

Monoclonal Anti-Sumo-2/3 (rat IgG2a isotype) is derived from the hybridoma 3H12 produced by the fusion of mouse myeloma cells and splenocytes from rat immunized with a human SUMO3 fusion protein.

Small ubiquitin-like modifier 3 (SUMO3) is encoded by the gene mapped to human chromosome 21q22.3. The protein belongs to the ubiquitin-like protein family and is expressed mainly in cytoplasm.

Immunogène

human SUMO3 fusion protein

Application

Monoclonal Anti-Sumo-2/3 has been used in immunoblotting and immunocytochemistry.

Actions biochimiques/physiologiques

Small ubiquitin-like modifier (SUMO) was identified as a post-translational protein modifier.

Small ubiquitin-like modifier 3 (SUMO3) plays a vital role in enhancing cellular responses to environmental stress. It acts as a key element of the leukemogenic network in transient myeloproliferative disorder (TMD) of the newborn/acute megakaryoblastic leukaemia (AMKL).

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable