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Key Documents

SAB2501669

Sigma-Aldrich

Anti-CASP3 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

HGNC:1504, caspase 3, caspase 3, apoptosis-related cysteine peptidase, caspase 3, apoptosis-related cysteine protease

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

goat

Niveau de qualité

100

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

canine, mouse, human, rat

Technique(s)

indirect ELISA: suitable
western blot: suitable

Numéro d'accès UniProt

P42574

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... CASP3(836)

Immunogène

Peptide with sequence C-RDVSKEDHSKRS, from the internal region of the protein sequence according toNP_004337.2; NP_116786.1

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

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Description
Tarif

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Wan Wang et al.
Journal of controlled release : official journal of the Controlled Release Society, 191, 4-14 (2014-05-02)
αB-Crystallin is a protein chaperone with anti-apoptotic and anti-inflammatory activity that is apically secreted in exosomes by polarized human retinal pigment epithelium. A 20 amino acid mini-peptide derived from residues 73-92 of αB-crystallin protects human retinal pigment epithelial (RPE) cells
Laura Masuelli et al.
Journal of translational medicine, 12, 122-122 (2014-06-03)
The antitumor activity induced by intratumoral vaccination with poxvirus expressing a tumor antigen was shown to be superior to that induced by subcutaneous vaccination. Salivary gland carcinomas overexpress ErbB2. Trastuzumab, a monoclonal antibody to ErbB2, was proposed for salivary gland
Jia-Ren Liu et al.
Shock (Augusta, Ga.), 42(6), 532-539 (2014-07-31)
Macrophage 1 antigen (Mac-1, CD11bCD18) is a leukocyte adhesion molecule that is involved in many functions including leukocyte recruitment, phagocytosis, and neutrophil apoptosis. The previous report of mild polymicrobial, abdominal sepsis showed that the administration of anti-CD11b-blocking antibody administration attenuated
Lars Vereecke et al.
Nature communications, 5, 5103-5103 (2014-10-01)
The transcription factor NF-κB is indispensable for intestinal immune homeostasis, but contributes to chronic inflammation and inflammatory bowel disease (IBD). A20, an inhibitor of both NF-κB and apoptotic signalling, was identified as a susceptibility gene for multiple inflammatory diseases, including
Kevin Hollevoet et al.
Molecular cancer therapeutics, 13(8), 2040-2049 (2014-06-15)
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, and new therapies are needed. RG7787 is a novel low-immunogenic antimesothelin recombinant immunotoxin (RIT), engineered to overcome the limitations of SS1P, a RIT now in clinical trials. In vitro activity was evaluated
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