S4776
Somatotropin from human pituitary
recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder
Synonyme(s) :
STH
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About This Item
Forme:
lyophilized powder
Essai:
≥95% (SDS-PAGE)
Produits recommandés
Produit recombinant
expressed in E. coli
Niveau de qualité
Stérilité
non-sterile
Essai
≥95% (SDS-PAGE)
Forme
lyophilized powder
Puissance
0.025-0.1 ng/mL cell proliferation using Nb2-11 cells per bioactivity ED50
Poids mol.
predicted mol wt ~22 kDa
drug control
Home Office Schedule 4.2
Impuretés
endotoxin, tested
Solubilité
PBS: 0.100 mL, clear, colorless (with 0.1% BSA )
Conditions d'expédition
ambient
Température de stockage
−20°C
Description générale
Somatotropin or growth hormone is a peptide hormone that is secreted by the anterior pituitary gland. It is essential for growth. The hormone increases muscle mass, reduces fat mass, helps in maintaining normal blood glucose levels and also promotes a balanced lipid profile.
Application
Somatotropin or growth hormone has been used to study the molecular interactions of ephrin type-A receptor 4 precursor (EphA4) with the growth hormone receptor. It has also been used to induce differentiation in mammary epithelial cell line HC11.
Actions biochimiques/physiologiques
Increases mass of most tissues by increasing cell number rather than cell size, mobilizes fat stores.
Forme physique
Lyophilized from a 0.2 μm filtered solution in TBS (20 mM Tris, 0.15 M NaCl, pH 8.5) containing 50 μg of BSA per 1 μg of cytokine.
Reconstitution
It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 10 μg/mL.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Yun Pang et al.
Kidney international, 90(6), 1357-1367 (2016-10-18)
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by overproduction of numerous autoantibodies. Many studies have sought to identify such biomarkers to distinguish patients with active lupus nephritis from SLE patients without renal involvement. Because antibodies to complement C1q
Molecular interactions of EphA4, growth hormone receptor, Janus kinase 2, and signal transducer and activator of transcription 5B
Takahiro Sawada
PLoS ONE (2017)
Somatotropin in the treatment of growth hormone deficiency and Turner syndrome in pediatric patients: a review
Christina Southern Reh
Clinical Pharmacology & Biopharmaceutics (2010)
Lina Pednekar et al.
Frontiers in immunology, 7, 600-600 (2017-01-10)
Dendritic cells (DCs) are the most potent antigen-presenting cells capable of priming naïve T-cells. Its C-type lectin receptor, DC-SIGN, regulates a wide range of immune functions. Along with its role in HIV-1 pathogenesis through complement opsonization of the virus, DC-SIGN
Quantitative analysis of the expression of whey acidic protein (WAP) mRNA in the prolactin-responsive mouse mammary gland epithelial cell line, HC11
Kawamata, Yuji, et al
Journal of Reproduction and Development (2001)
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