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RAB0537

Human FABP2 / Fatty Acid-Binding Protein, Intestinal ELISA Kit

Name: Human FABP2 / Fatty Acid-Binding Protein, Intestinal ELISA Kit
Brand: SIGMA

for serum, plasma, cell culture supernatants and urine

Synonyme(s) :

FABP2 ELISA Kit, Intestinal FABP2 Detection

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About This Item

Code UNSPSC :

41116158

Nomenclature NACRES :

NA.32

Espèces réactives

human

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable

Entrée

sample type plasma
sample type serum
sample type urine
sample type cell culture supernatant(s)

assay range

inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 25 pg/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... FABP2(2169)

Description générale

The antibody pair provided in this kit detects Intestinal, Human Fatty Acid-Binding Protein in serum, plasma, cell culture supernatants, and urine.

Fatty acid-binding protein (FABP2) is an intracellular protein, encoded by the gene mapped to human chromosome 4q28–q31.It is expressed in intestinal enterocytes. FABP2 codes for intestinal FABP (I-FABP).

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Actions biochimiques/physiologiques

Fatty acid-binding protein (FABP2) plays a vital role in the absorption and intracellular migration of dietary long-chain fatty acids. It also helps in the metabolism of fatty acids. FABP2 acts as a candidate gene for diabetes and insulin resistance. It is also implicated in lipid metabolism and adipogenesis.

Autres remarques

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Pictogrammes

GHS05

Mention d'avertissement

Warning

Mentions de danger

H290

Conseils de prudence

P234 - P390

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets.

Furuhashi M and Gokhan S H

Nature Reviews. Drug Discovery, 7(6), 489-489 (2008)

Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials.

Nicole U Stoffel et al.

The Lancet. Haematology, 4(11), e524-e533 (2017-10-17)

Current guidelines to treat iron deficiency recommend daily provision of ferrous iron divided through the day to increase absorption. However, daily dosing and split dosing might increase serum hepcidin and decrease iron absorption from subsequent doses. Our study aim was

Bifidobacteriumbreve Bif195 Protects Against Small-Intestinal Damage Caused by Acetylsalicylic Acid in Healthy Volunteers.

Brynjulf Mortensen et al.

Gastroenterology, 157(3), 637-646 (2019-05-17)

Enteropathy and small-intestinal ulcers are common adverse effects of nonsteroidal anti-inflammatory drugs such as acetylsalicylic acid (ASA). Safe, cytoprotective strategies are needed to reduce this risk. Specific bifidobacteria might have cytoprotective activities, but little is known about these effects in

Low Peripheral T Follicular Helper Cells in Perinatally HIV-Infected Children Correlate With Advancing HIV Disease.

Bret McCarty et al.

Frontiers in immunology, 9, 1901-1901 (2018-09-11)

T follicular helper (Tfh) cells are crucial for B cell differentiation and antigen-specific antibody production. Dysregulation of Tfh-mediated B cell help weakens B cell responses in HIV infection. Moreover, Tfh cells in the lymph node and peripheral blood comprise a

Intestinal Fatty Acid Binding Protein is Associated With Mortality in Patients With Acute Heart Failure or Cardiogenic Shock.

Stefan P Kastl et al.

Shock (Augusta, Ga.), 51(4), 410-415 (2018-05-31)

Acute heart failure and cardiogenic shock are associated with an impaired intestinal perfusion, which may lead to a release of cytoplasmatic proteins by hypoxic epithelial injury. Intestinal fatty acid binding protein (iFABP), highly specific for the small bowel enterocyte, may

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