R0655

Anti-Ribosomal Protein L26 (N-terminal) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-RPL26
• Numéro MDL: MFCD09265375
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 17 kDa
• Espèces réactives: mouse, human, rat
• Concentration: ~1 mg/mL
• Technique(s): immunoprecipitation (IP): 5-10 μg using HEK-293T cell lysates; indirect immunofluorescence: 5-10 μg/mL using paraformaldehye-fixed HeLa cells; western blot: 0.5-1 μg/mL using HEK-293T cell extracts
• Numéro d'accès UniProt: P61254
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... RPL26(6154) ; mouse ... Rpl26(19941) ; rat ... Rpl26(287417)

Description

Description générale

RPL26 (ribosomal protein L26) is located on chromosome 17. It codes for a 145-amino-acid long protein and has four exons. It is present on the large ribosomal subunit.

Ribosomal protein L26 is one of the large ribosomal subunit proteins.

Spécificité

Anti-Ribosomal Protein L26 (N-terminal) specificallyrecognizes human Ribosomal Protein L26.

Immunogène

synthetic peptide corresponding to amino acids 1-17 of human ribosomal protein L26, conjugated to KLH via a C-terminal added cysteine residue. The sequence is conserved in human, rat, and mouse.

Application

Anti-Ribosomal Protein L26 (N-terminal) antibody produced in rabbit has been used in:

• immunoblotting
• immunoprecipitation
• immunostaining
• immunofluorescence
• coimmunoprecipitation analysis

Actions biochimiques/physiologiques

RPL26 (ribosomal protein L26) regulates the expression of p73. It plays an important role in translation and stability of ribosomes. RPL26 frameshift mutation can cause several physical abnormalities.

Ribosomal proteins are implicated in mRNA recognition, tRNA recognition and decoding and nuclear export. It was shown together with nucleolin to bind to the 5′ untranslated region of p53 mRNA and to control p53 translation and induction after DNA damage.

Forme physique

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)