PLA0181

Rabbit anti-PSF/SFPQ Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonyme(s) : 100 kDa DNA-pairing protein, 100 kDa subunit, DNA-binding p52/p100 complex, POMP100, PPP1R140, PSF, PTB-associated splicing factor, PTB-associated-splicing factor, hPOMp100, polypyrimidine tract binding protein associated, polypyrimidine tract-binding protein-associated splicing factor, polypyrimidine tract-binding protein-associated-splicing factor, protein phosphatase 1, regulatory subunit 140, splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated), splicing factor proline/glutamine rich (polypyrimidine tract-binding protein-associated), splicing factor proline/glutamine-rich
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Qualité: Powered by Bethyl Laboratories, Inc.
• Espèces réactives: human, mouse
• Technique(s): immunohistochemistry: 1:100- 1:500; immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:2,000- 1:10,000
• Numéro d'accès: NP_005057.1
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: rabbit ... PSF/SFPQ(6421)

Description

Immunogène

The epitope recognized by PLA0181 maps to a region between residue 225 and 275 of human Polypyrimidine tract-binding protein-associated-splicing factor (Splicing factor, proline- and glutamine-rich) using the numbering given in entry NP_005057.1 (GeneID 6421).

Forme physique

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Autres remarques

PSF/SFPQ is a multifunctional protein know to participate in a variety of nuclear processes and may function to link transcription and pre-mRNA processing. PSF/SFPQ bears an RNA recognition motif (RRM) further indicating its role in post-transcriptional processes. PSF has been shown to associate with p54nrb/NonO to modulate androgen receptor-mediated transcription. Additionally, it has recently been show to associate with XRN2 and p54nrb/NonO to facilitate pre-mRNA 3′ processing and transcription termination.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable