PLA0118
Rabbit anti-Phospho RPS6 (S235/236) Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
Synonyme(s) :
40S ribosomal protein S6, S6, phosphoprotein NP33
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About This Item
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
affinity purified immunoglobulin
Type de produit anticorps
primary antibodies
Qualité
Powered by Bethyl Laboratories, Inc.
Espèces réactives
human
Technique(s)
western blot: 1:2,500-1:10,000
Numéro d'accès
NP_001001.2
Conditions d'expédition
wet ice
Température de stockage
2-8°C
Informations sur le gène
human ... RPS6(6194)
Immunogène
Immunogen for PLA0118 was a phosphorylated synthetic peptide, which represented a portion of human Ribosomal Protein S6 (GeneID 6194) around serine 235 and serine 236 according to the numbering given in entry NP_001001.2.
Forme physique
Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide
Autres remarques
Ribosomal protein S6 (RPS6) is a component of the 40S ribosomal subunit. Ribosomes are composed of a small 40S subunit and a large 60S subunit that function to catalyze protein synthesis. RPS6 is phosphorylated by many cellular kinases including ribosomal protein S6 kinase that is regulated via the mammalian target of rapamycin (mTOR) pathway. RPS6 has been demonstrated to be important in regulating cell size, glucose homeostasis, and translational control of mRNA.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Wei Kang et al.
Journal of translational medicine, 12, 281-281 (2014-10-08)
Aberrant AKT activation contributes to gastric cancer cell survival and chemotherapy resistance, however its regulation is poorly understood. microRNAs have been established to be important regulators in gastric carcinogenesis. Here, we showed the functional role and putative target of let-7b
Zachary A Knight et al.
eLife, 3, e01913-e01913 (2014-09-10)
Red blood cells (RBC) must coordinate their rate of growth and proliferation with the availability of nutrients, such as iron, but the signaling mechanisms that link the nutritional state to RBC growth are incompletely understood. We performed a screen for
H Hamidi et al.
British journal of cancer, 111(9), 1788-1801 (2014-08-29)
To study the molecular mechanism regulating sensitivity to MEK inhibition in pancreatic cancer cell lines. A growth inhibition assay determined sensitivity to MEK162 in a panel of 29 pancreatic cancer cell lines. For the same panel, KRAS mutational status and
Aaron M Nadon et al.
The American journal of pathology, 184(9), 2382-2389 (2014-07-13)
The mechanistic target of rapamycin (mTOR) is a central regulator of cellular responses to environmental stress. mTOR (and its primary complex mTORC1) is, therefore, ideally positioned to regulate lung inflammatory responses to an environmental insult, a function directly relevant to
Djalila Mekahli et al.
Pflugers Archiv : European journal of physiology, 466(8), 1591-1604 (2013-11-07)
Autosomal dominant polycystic kidney disease (ADPKD) is caused by loss-of-function mutations in either PKD1 or PKD2 genes, which encode polycystin-1 (TRPP1) and polycystin-2 (TRPP2), respectively. Increased activity of the mammalian target of rapamycin (mTOR) pathway has been shown in PKD1
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