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P7857

Sigma-Aldrich

Anti-P2X1 Purinergic Receptor antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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About This Item

Numéro MDL:
MFCD02097115
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

lyophilized powder

Espèces réactives

rat, human

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot (chemiluminescent): 1:200

Numéro d'accès UniProt

P51575

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... P2RX1(5023)
mouse ... P2rx1(18436)
rat ... P2rx1(25505)

Catégories apparentées

Immunogène

synthetic peptide corresponding to amino acids 382-399 of rat P2X1 (with additional N-terminal cysteine and serine). The epitope is highly conserved in mouse and human.

Forme physique

Lyophilized at ~0.6 mg/ml from a solution of phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
SLCM3889
SLCL0434
SLBP2723
059K1235
117K1257

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

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C M Chan et al.
The American journal of physiology, 274(4 Pt 2), F799-F804 (1998-05-12)
P2 receptors have been identified in rat kidney by autoradiography, using the radioligand [3H] alpha, beta-methylene ATP, and by immunohistochemistry, using a polyclonal antibody to the P2X1 purinoceptor. They have been localized to the vascular smooth muscle of intrarenal arteries
Derek M Kendig et al.
American journal of physiology. Renal physiology, 310(9), F909-F922 (2016-01-30)
Type II diabetes is the most prevalent form of diabetes. One of the primary complications of diabetes that significantly affects quality of life is bladder dysfunction. Many studies on diabetic bladder dysfunction have been performed in models of type I
G P Owens et al.
Molecular and cellular biology, 11(8), 4177-4188 (1991-08-01)
Programmed cell death is an essential cellular process that occurs in epithelial turnover, neural development, and regulation of cell populations of the immune system. Thymocytes undergo programmed cell death in response to several inductive stimuli, including exposure to glucocorticoids or
S Valera et al.
Nature, 371(6497), 516-519 (1994-10-06)
Extracellular ATP exerts its effects through P2 purinoceptors: these are ligand-gated ion channels (P2x) or G-protein-coupled receptors (P2Y, P2U). ATP at P2x receptors mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic
L Vulchanova et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(15), 8063-8067 (1996-07-23)
Several P2X receptor subunits were recently cloned; of these, one was cloned from the rat vas deferens (P2X1) and another from pheochromocytoma (PC12) cells differentiated with nerve growth factor (P2X2). Peptides corresponding to the C-terminal portions of the predicted receptor
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