P5155

Acide D-Pantothenique hemicalcium salt

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

• Synonyme(s) : (R)-(+)-N-(2,4-Dihydroxy-3,3-diméthyl-1-oxobutyl)-β-alanine hemicalcium salt, Vitamine B₅
• Formule linéaire : HOCH₂C(CH₃)₂CH(OH)CONHCH₂CH₂CO₂ ·1/2Ca
• Numéro CAS: 137-08-6
• Poids moléculaire : 238.27
• Numéro Beilstein : 3769272
• Numéro CE : 205-278-9
• Numéro MDL: MFCD00002766
• Code UNSPSC : 12352205
• eCl@ss : 34058012
• ID de substance PubChem : 24898601
• Nomenclature NACRES : NA.75

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Gamme de produits: BioReagent
• Pureté: ≥98% (TLC)
• Forme: powder
• Poids mol.: M_w 238.27 g/mol
• Technique(s): cell culture | insect: suitable; cell culture | mammalian: suitable; cell culture | plant: suitable
• Couleur: white to off-white
• pH: 7.0-8 (25 °C, 50 g/L)
• Solubilité: water: soluble 50 mg/mL, clear, colorless
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO
• InChI: 1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1
• Clé InChI: FAPWYRCQGJNNSJ-UBKPKTQASA-L

Description

Description générale

Plants and microorganisms, such as Escherichia coli are the major sources of D-pantothenic acid. It is water soluble and quite stable to heating.

Application

D-Pantothenic acid hemicalcium salt has been used:

• as a component of FMX-turbodoma- derived media
• as a supplement in DMEM (Dulbecco′s modified eagle media)/F-12 used for cell proliferation
• as a supplement in preadipocyte media

Précurseur dans la biosynthèse du coenzyme A.

Actions biochimiques/physiologiques

Along with coenzyme A (CoA, D-pantothenic acid is a precursor for acyl carrier protein. These are essential cofactors involved in fat, protein and carbohydrate metabolism. It also participates in the formation of acetylcholine neurotransmitter. D-pantothenic acid is considered as a source of nutrition and possesses immune function by mediating antibody formation. The production of cortisone is supported by D-pantothenic acid. It is essential for adrenal gland activity.

Propriétés physiques

En raison du caractère instable, hygroscopique, de l′acide libre, on utilise le sel de calcium.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)