N8159
Albumin, Nitrated from bovine serum
lyophilized powder
Synonyme(s) :
Nitrated BSA
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About This Item
Produits recommandés
Source biologique
bovine
Niveau de qualité
Forme
lyophilized powder
Technique(s)
immunoblotting: suitable
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Température de stockage
−20°C
Informations sur le gène
bovine ... ALB(280717)
Description générale
Albumin, Nitrated (Nitrated BSA), is prepared by chemical modification of bovine serum albumin (BSA) by peroxynitrite. Peroxynitrite (ONOO-), a potent oxidant is an important member of the family of reactive oxygen and nitrogen species.
Application
Positive control in immunoblotting assays for Anti-Nitrotyrosine (Sigma Product Number N 0409).
Actions biochimiques/physiologiques
Peroxynitrite promotes the nitration of tyrosine residues in proteins linked, oxidation of redox metal centers, DNA, lipids and nitrosation of cysteine residues in proteins, suggesting that peroxynitrite plays a major role in oxidative cellular damage. Peroxynitrite has been implicated in the pathogenesis of several inflammatory, infectious and degenerative human disease. These include neurological conditions such as Alzheimer′s disease, amyotrophic lateral sclerosis (ALS), the pathogenesis of asthma, atherosclerosis, and a variety of conditions precipitated by endothelial injury.
Forme physique
Lyophilized from 0.01 M phosphate buffered saline, pH 7.4
Notes préparatoires
Bovine serum albumin (BSA) nitrated with peroxynitrite.
Remarque sur l'analyse
Does not contain sodium azide
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Inhibitory effect of isoflavones on peroxynitrite-mediated low-density lipoprotein oxidation
Bioscience, Biotechnology, and Biochemistry, 66(1), 22-28 (2002)
The Intracellular Redox Stress Caused by Hexavalent Chromium is Selective for Proteins that Have Key Roles in Cell Survival and Thiol Redox Control
Toxicology (2011)
Nitric oxide and peroxynitrite in health and disease
Physiological Reviews, 87(1), 315-424 (2007)
Antioxidants (Basel, Switzerland), 10(1) (2021-01-13)
Selenium (Se) enrichment of Stevia rebaudiana Bertoni can serve a dual purpose, on the one hand to increase plant biomass and stress tolerance and on the other hand to produce Se fortified plant-based food. Foliar Se spraying (0, 6, 8
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