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N1377

Sigma-Aldrich

4-Nitrophenyl α-D-glucopyranoside

≥99%

Synonyme(s) :

p-Nitrophenyl α-D-glucopyranoside

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About This Item

Formule empirique (notation de Hill):
C12H15NO8
Numéro CAS:
3767-28-0
Poids moléculaire :
301.25
Numéro Beilstein :
92212
Numéro CE :
223-189-3
Numéro MDL:
MFCD00064088
Code UNSPSC :
12352204
ID de substance PubChem :
24897484
Nomenclature NACRES :
NA.32

Niveau de qualité

300

Pureté

≥99%

Forme

powder or crystals

Solubilité

methanol: 20 mg/mL, clear to very slightly hazy, colorless to greenish-yellow

Température de stockage

−20°C

Chaîne SMILES 

OC[C@H]1O[C@H](Oc2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11-,12+/m1/s1

Clé InChI

IFBHRQDFSNCLOZ-ZIQFBCGOSA-N

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Application

4-Nitrophenyl ǥ-D-glucopyranoside has been used as a substrate in an ǥ-glucosidase inhibition assay.

Actions biochimiques/physiologiques

4-Nitrophenyl ǥ-D-glucopyranoside serves as a substrate for glycosidases. Upon cleavage, the substrate is converted to a yellow-colored product.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Jaegoo Kim et al.
World journal of microbiology & biotechnology, 34(11), 167-167 (2018-11-02)
Candida albicans is a major invasive pathogen, and the development of strains resistant to conventional antifungal agents has been reported in recent years. We evaluated the antifungal activity of 44 compounds against Candida strains. Magnoflorine showed the highest growth inhibitory
Sajjad Esmaeili et al.
Bioorganic chemistry, 88, 102972-102972 (2019-05-13)
Dipyridamole (DP) elevates cyclic Adenosine Monophosphate (cAMP) levels in platelets, erythrocytes, and endothelial cells and also blocks adenosine reuptake. It is used to dilate blood vessels in people with peripheral arterial disease and coronary artery disease (CAD). The flexible backbone
P S Unnikrishnan et al.
Pharmacognosy magazine, 11(Suppl 4), S511-S515 (2016-03-26)
In the continuing search for safe and efficient antidiabetic drug, marine algae become important source which provide several compounds of immense therapeutic potential. Alpha-amylase, alpha-glucosidase inhibitors, and antioxidant compounds are known to manage diabetes and have received much attention recently.
Faryal Chaudhry et al.
Bioorganic chemistry, 82, 267-273 (2018-11-06)
Herein, substituted imidazole-pyrazole hybrids (2a-2n) were prepared via a multi component reaction employing pyrazole-4-carbaldehydes (1a-1d), ammonium acetate, benzil and arylamines as reactants. All the new compounds were characterized through their spectral and elemental analyses. Further these compounds were tested against
Bita Amiri et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 138, 105040-105040 (2019-08-11)
Antibiotics are effective drugs that are used to treat infectious diseases either by killing bacteria or slowing down their growth. The well-adapted structural features of antibiotics for the inhibition/activation of enzymes include several available hydrogen bond (H-bond) acceptors and donors
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