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M8890

Sigma-Aldrich

Anticorps anti-IgG de souris (molécule complète) antibody produced in goat

IgG fraction of antiserum, lyophilized powder

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About This Item

Numéro CE :
Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

goat

Niveau de qualité

Conjugué

unconjugated

Forme d'anticorps

IgG fraction of antiserum

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Forme

lyophilized powder

Conditionnement

vial of 2 mL lyophilized antiserum

Technique(s)

Ouchterlony double diffusion: 1:8

Température de stockage

2-8°C

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Application

Anti-Mouse IgG (whole molecule) antibody produced in goat was used to immunoprecipitate bovine brain adenylyl cyclase. It was used α-defensin isoforms in the plasma of type I diabetic patients by radio immune assay.

Actions biochimiques/physiologiques

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Forme physique

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

Reconstitution

Reconstitute with 2 mL deionized water.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Consulter la Bibliothèque de documents

Gowsini Joseph et al.
The Journal of clinical endocrinology and metabolism, 93(4), 1470-1475 (2008-01-24)
alpha-Defensins are antimicrobial peptides of the innate immune system. In addition, experimental evidence suggests that alpha-defensins are proatherogenic. The objective of the study was to examine the predictive value of plasma alpha-defensin as a clinical marker of cardiovascular disease (CVD)
S Mollner et al.
European journal of biochemistry, 171(1-2), 265-271 (1988-01-15)
Four monoclonal antibodies, raised against the 115-kDa adenylyl cyclase from bovine brain [Pfeuffer, E. et al. (1985) EMBO J. 4, 3675-3679] have been selected and designated BBC-1 to BBC-4. BBC-1 and BBC-3 are highly specific for the 115-kDa enzyme from
Julius Grzeschik et al.
Biotechnology journal, 14(4), e1800466-e1800466 (2018-10-24)
Yeast surface display emerged as a viable tool for the generation of human and murine monoclonal antibodies. This platform technology enables the careful definition of selection conditions, the potential for high-throughput screening, as well as the isolation of antibodies recognizing
L L Peters et al.
Blood, 76(4), 745-754 (1990-08-15)
A new autosomal recessive mouse mutation, scat (severe combined anemia and thrombocytopenia), causes intermittent episodes of severe bleeding in the homozygote. At birth, affected mice are pale with intradermal petechiae and bruises on exposed surfaces. Central nervous system (CNS) bleeding
M Saraheimo et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 23(3), 914-918 (2007-11-16)
Diabetic nephropathy is associated with low-grade inflammation and activation of the complement system. Defensins, as part of the innate immune system, may play a regulatory role in the complement cascade and may also augment the production of proinflammatory cytokines. The

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