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M2939

Sigma-Aldrich

Methyl arachidonyl fluorophosphonate

≥98%, methyl acetate solution (10 mg/mL)

Synonyme(s) :

MAPF, Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester

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About This Item

Formule empirique (notation de Hill):
C21H36FO2P
Numéro CAS:
188404-10-6
Poids moléculaire :
370.48
Numéro CE :
201-185-2
Numéro MDL:
MFCD03095722
Code UNSPSC :
41106300
ID de substance PubChem :
329817956
Nomenclature NACRES :
NA.77

Niveau de qualité

200

Pureté

≥98%

Forme

methyl acetate solution (10 mg/mL)

Conditions d'expédition

dry ice

Température de stockage

−70°C

Chaîne SMILES 

CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCP(F)(=O)OC

InChI

1S/C21H36FO2P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(22,23)24-2/h7-8,10-11,13-14,16-17H,3-6,9,12,15,18-21H2,1-2H3/b8-7-,11-10-,14-13-,17-16-

Clé InChI

KWKZCGMJGHHOKJ-ZKWNWVNESA-N

Actions biochimiques/physiologiques

MAFP is a selective, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic phospholipase A2, but not secretory phospholipase A2. MAFP is also a potent acetylcholinesterase inhibitor.

Notes préparatoires

To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice.

Pictogrammes

FlameExclamation mark
GHS02,GHS07

Mention d'avertissement

Danger

Mentions de danger

H225,H319,H336

Classification des risques

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Organes cibles

Central nervous system

Risques supp

EUH066

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

3.2 °F - closed cup

Point d'éclair (°C)

-16 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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