Accéder au contenu
MilliporeSigma
Toutes les photos(1)

Key Documents

Autres documents

LO1280

Sigma-Aldrich

LOPAC®1280

Synonyme(s) :

Library of Pharmacologically Active Compounds

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Code UNSPSC :
12352200

Forme

liquid

Niveau de qualité

100

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (250 μl at 10 mM in DMSO).

Application

LOPAC®1280 has been used:
  • in the screening of novel inhibitors for chemotaxis/ migration using Dictyostelium as a model
  • to test the ability to modulate and to measure forskolin-stimulated cAMP levels in CHO-hCB2 cells and to modulate ligand-induced receptor/β-arrestin interaction
  • in screening of small molecules for activating bone morphogenetic protein (BMP) signaling
  • in screening of compounds that plays a role in regulating subcellular localization of nitric oxide associated protein 1 (NOA1) protein

Caractéristiques et avantages

Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:

  • Apoptosis
  • G Proteins & Cyclic Nucleotides
  • Gene Regulation & Expression
  • Ion Channels
  • Lipid Signaling
  • Multi-Drug Resistance
  • Neurotransmission
  • Phosphorylation
SDFile provided to construct a database containing:
  • Structure
  • Primary Name
  • Secondary Name
  • Pharmacological Activity
  • Product Number
  • Rack Position
Collection of 1,280 Pharmacologically-Active Sigma Compounds
To request a list of components, please visit sigma.com/LOPAC

Autres remarques

For sale in the U.S. only. Customers outside of the U.S. should refer to product code LO3300.

Informations légales

LOPAC is a registered trademark of Merck KGaA, Darmstadt, Germany

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Lact. - Muta. 1B - Repr. 1A - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 2

Code de la classe de stockage

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

188.6 °F - closed cup

Point d'éclair (°C)

87 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 2

1 of 2

Bicalutamide (CDX) ≥98% (HPLC), powder

Sigma-Aldrich

B9061

Bicalutamide (CDX)

Cetirizine dihydrochloride ≥98% (HPLC)

Sigma-Aldrich

C3618

Cetirizine dihydrochloride

Karen Camargo-Sosa et al.
PLoS genetics, 15(2), e1007941-e1007941 (2019-02-28)
Skin pigment patterns are important, being under strong selection for multiple roles including camouflage and UV protection. Pigment cells underlying these patterns form from adult pigment stem cells (APSCs). In zebrafish, APSCs derive from embryonic neural crest cells, but sit
NOA1, a novel ClpXP substrate, takes an unexpected nuclear detour prior to mitochondrial import
Al-Furoukh N, et al.
PLoS ONE, 9(7), e103141-e103141 (2014)
Identification of small molecule activators of BMP signaling
Vrijens K, et al.
PLoS ONE, 8(3), e59045-e59045 (2013)
A Unique High-Throughput Assay to Identify Novel Small Molecule Inhibitors of Chemotaxis and Migration
Liao XH and Kimmel AR
Current Protocols in Cell Biology, 74(1), 12-11 (2017)
Clara Lettl et al.
Frontiers in cellular and infection microbiology, 10, 602958-602958 (2021-01-05)
Type IV secretion systems are protein secretion machineries that are frequently used by pathogenic bacteria to inject their virulence factors into target cells of their respective hosts. In the case of the human gastric pathogen Helicobacter pylori, the cytotoxin-associated gene
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique