L0302511

ETT Activator

• Synonyme(s) : 5-(Ethylthio)-1H-tetrazole, 5-(Ethylthio)tetrazole solution
• Numéro MDL: MFCD00068733
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.21

Propriétés

• Type: for DNA synthesis
• Niveau de qualité: 200
• Gamme de produits: Proligo Reagents
• Conditionnement: pkg of 4 × 2.5 L L0302511-04
• Concentration: 39-43 g/L (titration)
• Impuretés: ≤30 ppm water content (Karl Fischer)
• Couleur: clear
• Chaîne SMILES: CCSc1nnn[nH]1
• InChI: 1S/C3H6N4S/c1-2-8-3-4-6-7-5-3/h2H2,1H3,(H,4,5,6,7)
• Clé InChI: GONFBOIJNUKKST-UHFFFAOYSA-N

Description

Description générale

ETT activator is an activator solution containing 5-(Ethylthio)-1H-tetrazole – a powerful activator – in acetonitrile. It is mixed with phosphoramidite during the extension step in which it reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.

Application

ETT activator has been used in the fast and low-cost synthesis of photolithographic DNA microarrays.

Informations sur la sécurité

• Pictogrammes: GHS02,GHS05,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H225,H302 + H312 + H332,H315,H318
• Conseils de prudence: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 35.6 °F
• Point d'éclair (°C): 2 °C