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Key Documents

I1536

Sigma-Aldrich

Isoorientin

≥98% (HPLC)

Synonyme(s) :

Homoorientin, Luteolin 6-C-β-D-glucoside, Luteolin 6-C-glucoside

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About This Item

Formule empirique (notation de Hill):
C21H20O11
Numéro CAS:
Poids moléculaire :
448.38
Numéro MDL:
Code UNSPSC :
12352205
ID de substance PubChem :
Nomenclature NACRES :
NA.25

Source biologique

leaves (Phyllostachya Nigra)

Niveau de qualité

Pureté

≥98% (HPLC)

Forme

powder

Technique(s)

HPLC: suitable

Couleur

yellow

Pf

236 - 237  °C ( (457 - 459 °F))

Solubilité

methanol: 5 mg/mL, clear, colorless to yellow

Température de stockage

2-8°C

Chaîne SMILES 

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3OC(=CC(=O)c3c2O)c4ccc(O)c(O)c4

InChI

1S/C21H20O11/c22-6-14-17(27)19(29)20(30)21(32-14)16-11(26)5-13-15(18(16)28)10(25)4-12(31-13)7-1-2-8(23)9(24)3-7/h1-5,14,17,19-24,26-30H,6H2/t14-,17-,19+,20-,21+/m1/s1

Clé InChI

ODBRNZZJSYPIDI-VJXVFPJBSA-N

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Application


  • Exploring the therapeutic potential of isoorientin in the treatment of osteoporosis: a study using network pharmacology and experimental validation.: This research investigates isoorientin′s therapeutic potential in osteoporosis treatment, using network pharmacology and experimental methods to validate its efficacy (Zhang B et al., 2024).

Actions biochimiques/physiologiques

C-glycosyl flavone with anti-inflammatory, antimicrobial and antioxidant properties. Induces antioxidant response through PI3K singaling.

Autres remarques

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Les clients ont également consulté

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Dong-Seon Kim et al.
Planta medica, 76(7), 678-682 (2009-12-05)
We aimed to find antiallergic agents from natural sources using mast cells activated during allergic reaction. We screened over 2000 plants for blockade of histamine release and identified two of them, S. baicalenesis and P. edulis. Bioassay-guided fractionation led to
Mala Ranghoo-Sanmukhiya et al.
Phytochemical analysis : PCA, 21(6), 566-574 (2010-09-08)
Aloe tormentorii, A. purpurea and A. macra are used as multipurpose folk medicines in Réunion and Mauritius Islands and are mistaken for the introduced Aloe vera. To compare the phytochemical, antimicrobial and DNA profiles of Aloe endemic to Mauritius and
Roxana Orrego et al.
Molecules (Basel, Switzerland), 14(10), 3906-3913 (2009-11-20)
This study assessed the inhibitory effect of three C-glycosylflavonoids from Cymbopogon citratus leaves--isoorientin (1), swertiajaponin (2) and isoorientin 2"-Orhamnoside (3)--on human LDL oxidation. Isolated LDL was incubated with compounds 1-3 and the kinetics of lipid peroxidation were assessed by conjugated
Li Yuan et al.
Toxicology and applied pharmacology, 265(1), 83-92 (2012-10-03)
Isoorientin (ISO) is a flavonoid compound that can be extracted from several plant species, such as Phyllostachys pubescens, Patrinia, and Drosophyllum lusitanicum; however, its biological activity remains poorly understood. The present study investigated the effects and putative mechanism of apoptosis
Severina Pacifico et al.
Journal of natural products, 73(12), 1973-1978 (2010-11-18)
Eight flavonoid C-glycosides, including three new analogues, have been isolated from leaf and root methanolic extracts of Petrorhagia velutina, a Mediterranean herbaceous plant. The antiproliferative activity against human hepatoblastoma cancer cell line HepG2 has been analyzed by the MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium

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