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H7157

Sigma-Aldrich

Anti-Hepatocyte Growth Factor antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonyme(s) :

Anti-HGF

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About This Item

Numéro MDL:
MFCD00212968
Code UNSPSC :
51111800
Nomenclature NACRES :
NA.41

Source biologique

goat

Niveau de qualité

100

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

lyophilized powder

Espèces réactives

human

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 15 μg/mL using human tissue
western blot: 0.1-0.2 μg/mL

Numéro d'accès UniProt

P14210

Application(s)

research pathology

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... HGF(3082)

Description générale

Hepatocyte Growth Factor (HGF) also refers as Scatter Factor and Hematopoietin A is a 82-85 kD potent mitogen for epithelial cells. It has a critical role in stimulating the growth of hepatocytes, epidermal keratinocytes, Mv1Lu (mink lung epithelial cells), renal tubular epithelial cells, epidermal melanocytes and BALB/MK (mouse keratinocytes) . Anti-Hepatocyte Growth Factor antibody can be used to neutralize the biological activity of recombinant human HGF (rhHGF). Goat anti-Hepatocyte Growth Factor antibody reacts specifically with recombinant human HGF (rhHGF).

Spécificité

The antibody will neutralize the biological activity of recombinant human HGF.

Immunogène

recombinant human HGF.

Application

Anti-Hepatocyte Growth Factor antibody can be used in immunohistochemistry and western blotting.

Forme physique

Lyophilized from 0.2 μm filtered solution of phosphate buffered saline, pH 7.4, containing 5% trehalose.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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D Kovacs et al.
The British journal of dermatology, 163(5), 1020-1027 (2010-07-29)
Cutaneous pigmentation is regulated by a complex melanogenic network in which both keratinocytes and fibroblasts synthesize growth factors and cytokines. Solar lentigo (SL) is characterized by hyperpigmented lesions occurring on photodamaged skin areas. Despite the association of SL to ultraviolet
Rosaria Cammarota et al.
Journal of translational medicine, 8, 112-112 (2010-11-10)
Colorectal cancer can be efficiently treated when found at early stages, thus the search for novel markers is of paramount importance. Since inflammation is associated with cancer progression and angiogenesis, we investigated expression of cytokines like IL-6 and other mediators
A Catizone et al.
Molecular and cellular endocrinology, 241(1-2), 32-40 (2005-06-21)
Hepatocyte growth factor regulates many cellular functions acting through c-met, its specific receptor with tyrosine kinase activity. We have previously reported that in prepubertal rats HGF is secreted in the seminiferous tubules by purified peritubular myoid cells whereas Sertoli cells
Hong-Zheng Zhang et al.
Endocrinology, 143(9), 3427-3434 (2002-08-24)
Epithelial-stromal cell interactions are important for normal development and function of the mouse mammary gland. The steroid hormone estrogen is required for epithelial cell proliferation and ductal development in vivo. Recent studies of estrogen receptor alpha knockout mice indicate that
R A Furlong
BioEssays : news and reviews in molecular, cellular and developmental biology, 14(9), 613-617 (1992-09-01)
Hepatocyte growth factor, a potent mitogen for epithelial and other cell types, and scatter factor, a stimulant of epithelial cell motility are identical. In addition to these mitogenic and motogenic functions, the factor has been shown to be an epithelial
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