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Key Documents

F5132

Sigma-Aldrich

Factor II from human plasma

lyophilized powder, 5-20 units/mg protein

Synonyme(s) :

Prothrombin

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About This Item

Numéro CAS:
9001-26-7
Numéro CE :
232-592-3
Numéro MDL:
MFCD00148143
Code UNSPSC :
12352200

Forme

lyophilized powder

Activité spécifique

5-20 units/mg protein

Numéro d'accès UniProt

P00734

Activité étrangère

factor X <0.01% of base activity
thrombin, none detected

Température de stockage

−20°C

Informations sur le gène

human ... F2(2147)

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Actions biochimiques/physiologiques

Plasma phospholipid binding protein; binds to endothelial cells, promotes clotting on the cell surfaces.

Définition de l'unité

One unit is the amount contained in one mL of normal human plasma.

Reconstitution

When reconstituted with 1 ml of deionized water, solution will contain the indicated activity in 0.5 M NaCl, 0.05 M Tris-HCl, pH 8.0.

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Maria M Aleman et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(8), 1829-1836 (2013-06-01)
Individuals with elevated prothrombin, including those with the prothrombin G20210A mutation, have increased risk of venous thrombosis. Although these individuals do not have increased circulating prothrombotic biomarkers, their plasma demonstrates increased tissue factor-dependent thrombin generation in vitro. The objectives of
Yuichiro Yanagida et al.
Surgery, 154(1), 48-57 (2013-05-21)
We tested the hypotheses that an increase in systemic thrombin activity occurs in both disseminated intravascular coagulation (DIC) with the fibrinolytic phenotype and in acute coagulopathy of trauma shock (ACoTS), and that the patients diagnosed as having ACoTS overlap or
Masahiko Tameda et al.
Cancer science, 104(6), 725-731 (2013-03-14)
Serum tumor markers, including α-fetoprotein (AFP) and des-γ-carboxy prothrombin (DCP), are currently used in the diagnosis of hepatocellular carcinoma (HCC). There is, however, an aberrant increase in serum DCP in patients with obstructive jaundice, vitamin K deficiency or who are
Marc A Bailey et al.
Journal of vascular surgery, 57(6), 1512-1518 (2013-03-16)
Abdominal aortic aneurysm (AAA) is associated with hypercoagulability, evidenced by increased markers of coagulation activation, including thrombin-antithrombin complex (TAT), prothrombin fragments 1 and 2 (F1+2), and D-dimer. Our aim was to compare the effect of endovascular aneurysm repair (EVAR) and
Atsushi Nanashima et al.
Anticancer research, 33(6), 2689-2697 (2013-06-12)
Although the protein-induced vitamin K absence or antagonist-II (PIVKA-II) is used as a prognostic marker in hepatocellular carcinoma (HCC), a newly-improved assay, NX-PVKA (PIVKA-II measured using P-11 and P-16 antibodies) and NX-PVKA-R (ratio of PIVKA-II and NX-PVKA), are more accurate
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