Accéder au contenu
MilliporeSigma
Toutes les photos(1)

Key Documents

View All Documentation

F1016

Sigma-Aldrich

Fenoterol hydrobromide

Synonyme(s) :

2-(3,5-Dihydroxyphenyl)-2-hydroxy-2′-(4-hydroxyphenyl)-1′-methyldiethylamine hydrobromide

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule empirique (notation de Hill):
C17H21NO4 · HBr
Numéro CAS:
1944-12-3
Poids moléculaire :
384.26
Numéro CE :
217-742-8
Numéro MDL:
MFCD00079288
Code UNSPSC :
41116107
ID de substance PubChem :
24278431
Nomenclature NACRES :
NA.77

Auteur

Boehringer Ingelheim

Chaîne SMILES 

Br[H].CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2

InChI

1S/C17H21NO4.BrH/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13;/h2-5,7-9,11,17-22H,6,10H2,1H3;1H

Clé InChI

SGZRQMALQBXAIQ-UHFFFAOYSA-N

Informations sur le gène

human ... ADRB2(154)

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Description générale

Fenoterol hydrobromide is a sympathomimetic drug. It is used to treat asthma, bronchitis and emphysema. Fenoterol administration might be linked to liver damage. It has anti-inflammatory effects on eosinophil function.

Application

Fenoterol hydrobromide has been used in chromatography-tandem mass spectrometry (LC&-MS-MS) for specific and sensitive detection of β-agonists (BAG).

Actions biochimiques/physiologiques

β2-adrenoceptor agonist; bronchodilator.

Caractéristiques et avantages

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Conseils de prudence

P301 + P312 + P330

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Krzysztof Jozwiak et al.
Chirality, 23 Suppl 1, E1-E6 (2011-05-28)
The β(2) adrenergic receptor (β(2)-AR) is a model system for studying the ligand recognition process in G protein-coupled receptors. Fenoterol (FEN) is a β(2)-AR selective agonist that has two centers of chirality and exists as four stereoisomers. Radioligand binding studies
Hegui Wang et al.
PloS one, 7(9), e46186-e46186 (2012-10-03)
Increasing evidence indicates that the rapid component of delayed rectifier potassium current (I(Kr)) is modulated by α- and β-adrenergic stimulation. However, the role and mechanism regulating I(Kr) through β(2)-adrenoreceptor (β-AR) stimulation in heart failure (HF) are unclear. In the present
Joanne Chung Yan Yeung et al.
Analytica chimica acta, 742, 37-44 (2012-08-14)
In vivo solid-phase microextraction (SPME) can be used to sample the circulating blood of animals without the need to withdraw a representative blood sample. In this study, in vivo SPME in combination with liquid-chromatography tandem mass spectrometry (LC-MS/MS) was used
T Katsunuma et al.
American journal of respiratory cell and molecular biology, 21(3), 409-417 (1999-08-26)
Neurokinin A (NKA) induces bronchoconstriction mediated by tachykinin NK(2) receptors in animals and humans, and may be increased in asthma. Because beta(2)-adrenoceptor agonists are the most widely used bronchodilators in asthma, we investigated the effects of the beta(2)-adrenoceptor agonist fenoterol
Ka-Pan Lam et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 22(4), 431-439 (2011-02-16)
Short-acting β2-adrenoreceptor agonist (SABA) is the major asthma reliever as indicated in the GINA guidelines. Regulated on activation, normal T expressed and secreted (RANTES) is a chemokine that attracts eosinophils, mast cells, and basophils toward site of allergic inflammation. Interferon
Afficher tous les articles scientifiques apparentés

Chromatograms

application for HPLC

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique