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F0257

Sigma-Aldrich

Anti-Mouse IgG (whole molecule)–FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-Mouse Fitc, Anti-Mouse Fitc - Anti-Mouse IgG (whole molecule)–FITC antibody produced in goat

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About This Item

Numéro MDL:
MFCD00162642
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

goat

Conjugué

FITC conjugate

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Technique(s)

direct immunofluorescence: 1:32

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

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Description générale

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to foetus through the placenta that is vital for immune defense of the neonate against infections. Mouse IgGs has four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3.

Immunogène

Purified mouse IgG

Application

Anti-Mouse IgG (whole molecule)-FITC antibody has been used in:
  • immunohistochemistry (1:200) (1:500)
  • immunofluorescence (1:100)(1:500)(1:200)
  • immunocytochemistry(1:1000)

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Amanda K Silva et al.
Molecular vision, 16, 36-45 (2010-01-14)
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Bluhm, W., F., et al.
American Journal of Physiology. Heart and Circulatory Physiology, 275(6), H2243-H2249 (1998)
Susana M Garcia et al.
Genes & development, 21(22), 3006-3016 (2007-11-17)
Protein homeostasis maintains proper intracellular balance by promoting protein folding and clearance mechanisms while minimizing the stress caused by the accumulation of misfolded and damaged proteins. Chronic expression of aggregation-prone proteins is deleterious to the cell and has been linked
Maruthachalam Ravi et al.
PLoS genetics, 7(6), e1002121-e1002121 (2011-06-23)
Centromere behavior is specialized in meiosis I, so that sister chromatids of homologous chromosomes are pulled toward the same side of the spindle (through kinetochore mono-orientation) and chromosome number is reduced. Factors required for mono-orientation have been identified in yeast.
Siu-Kei Chow et al.
ASN neuro, 2(1), e00026-e00026 (2009-12-17)
The contribution of astrocytes to the pathophysiology of AD (Alzheimer's disease) and the molecular and signalling mechanisms that potentially underlie them are still very poorly understood. However, there is mounting evidence that calcium dysregulation in astrocytes may be playing a
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