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Key Documents

E5757

Sigma-Aldrich

Methionine Enkephalin-Arg-Phe acetate salt hydrate

≥97% (HPLC)

Synonyme(s) :

MERF, Tyr-Gly-Gly-Phe-Met-Arg-Phe

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About This Item

Formule empirique (notation de Hill):
C42H56N10O9S · xC2H4O2 · yH2O
Poids moléculaire :
877.02 (anhydrous free base basis)
Numéro MDL:
Code UNSPSC :
12352209
ID de substance PubChem :
Nomenclature NACRES :
NA.32

Niveau de qualité

Pureté

≥97% (HPLC)

Température de stockage

−20°C

Chaîne SMILES 

O.CC(O)=O.CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc3ccccc3)C(O)=O

InChI

1S/C42H56N10O9S.C2H4O2.H2O/c1-62-20-18-32(39(58)50-31(13-8-19-46-42(44)45)38(57)52-34(41(60)61)23-27-11-6-3-7-12-27)51-40(59)33(22-26-9-4-2-5-10-26)49-36(55)25-47-35(54)24-48-37(56)30(43)21-28-14-16-29(53)17-15-28;1-2(3)4;/h2-7,9-12,14-17,30-34,53H,8,13,18-25,43H2,1H3,(H,47,54)(H,48,56)(H,49,55)(H,50,58)(H,51,59)(H,52,57)(H,60,61)(H4,44,45,46);1H3,(H,3,4);1H2/t30-,31-,32-,33-,34-;;/m0../s1

Clé InChI

WOWLRTTTXHINBL-AVEXNAMASA-N

Actions biochimiques/physiologiques

Endogenous opioid heptapeptide that is an agonist at μ, δ, and κ receptors; also binds to σ2 receptors.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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BMC genomics, 20(1), 497-497 (2019-06-19)
The introduction of genome-wide shRNA and CRISPR libraries has facilitated cell-based screens to identify loss-of-function mutations associated with a phenotype of interest. Approaches to perform analogous gain-of-function screens are less common, although some reports have utilized arrayed viral expression libraries
David L Phillips et al.
Cornea, 34(11), 1383-1386 (2015-09-24)
To evaluate the outcome of the Boston type 1 keratoprosthesis (KPro-1) in eyes with iridocorneal endothelial syndromes and failed keratoplasties. A retrospective review was performed of every eye with a history of iridocorneal endothelial syndrome and a failed corneal transplant
Mohideen Abdul Kader et al.
Ophthalmic genetics, 38(3), 222-225 (2016-06-30)
To both characterize the clinical features of large primary open angle glaucoma (POAG) pedigree from a village in southern India and to investigate the genetic basis of their disease. Eighty-four members of a large pedigree received complete eye examinations including

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