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Key Documents

B1645

Sigma-Aldrich

Anti-Bovine IgG (whole molecule) antibody produced in goat

whole antiserum

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

goat

Conjugué

unconjugated

Forme d'anticorps

whole antiserum

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Contient

15 mM sodium azide

Technique(s)

quantitative precipitin assay: 2.8 mg/mL

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Description générale

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids.

Spécificité

The antiserum shows a single arc of precipitation versus bovine serum and bovine IgG by immunoelectrophoresis (IEP). This antiserum has not been assayed for interspecies cross reactivity.

Application

Anti-Bovine IgG (whole molecule) antibody produced in goat has been used in:
  • quantitative precipitation assays and in various immunosensor methods to detect bovine IgG in serum and milk
  • immuno-reaction assay
  • indirect sandwich enzyme linked immunosorbent assay (ELISA)
It has also been used in immuno-reaction assay.

Actions biochimiques/physiologiques

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Forme physique

Supplied as a liquid with 0.1% sodium azide (see MSDS) as a preservative.

Notes préparatoires

treated to remove lipoproteins

Stockage et stabilité

For continuous use, store at 0-5 °C. For extended storage, solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" is not recommended. If slight turbidity occurs upon prolonged storage, clarify by centrifugation before use.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Mauro Tomassetti et al.
Journal of pharmaceutical and biomedical analysis, 73, 90-98 (2012-05-09)
Within the framework of research carried out by our team aimed at developing new immunological methods to determine proteins such as immunoglobulins G in different biological matrixes, for instance, serum and milk, tests were performed on several immunosensors based on
Bismuth film electrode as sensing platform for IgE-anti-IgE interactions
Anik U, et al.
Electroanalysis, 23(10), 2379-2385 (2011)
IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4
Avery DT, et al.
Journal of Immunology, 181(3), 1767-1779 (2008)
Placental transfer of IgG subclasses in a Japanese population.
Hashira S, et al.
Pediatrics International, 42(4) (2000)
Gestur Vidarsson et al.
Frontiers in immunology, 5, 520-520 (2014-11-05)
Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ in their constant region, particularly in their hinges and upper CH2 domains. These

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