A5285

Adenosine 5′-diphosphate monopotassium salt dihydrate

bacterial, ≥95%, powder

• Synonyme(s) : Adenosine 5′-Diphosphate Potassium Salt, ADP
• Formule empirique (notation de Hill): C₁₀H₁₄KN₅O₁₀P₂ · 2H₂O
• Numéro CAS: 72696-48-1
• Poids moléculaire : 501.32
• Numéro MDL: MFCD00066472
• Code UNSPSC : 41106305
• eCl@ss : 32160414
• ID de substance PubChem : 24890964
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: bacterial
• Pureté: ≥95%
• Forme: powder
• Température de stockage: −20°C
• Chaîne SMILES: [O-]P(OP(OC[C@H]([C@@H](O)[C@H]1O)O[C@H]1N2C3=C(N=C2)C(N)=NC=N3)(O)=O)(O)=O.[K+]
• InChI: 1S/C10H15N5O10P2.K/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
• Clé InChI: ZNCWUOPIJTUALR-MCDZGGTQSA-M
• Informations sur le gène: human ... HSP90AA1(3320) , P2RY1(5028)

Description

Description générale

Adenosine diphosphate (ADP) is a crucial component for energy flow in living organisms. Its structure consists of a sugar backbone connected to adenine and two phosphate groups attached to the fifth carbon atom of the ribose sugar. ADP serves a precursor for ATP biosynthesis. ADP acts as a weak platelet agonist, specifically targeting the P2Y receptor. However, ADP plays a vital role in platelet function by enhancing the effects of other platelet agonists and promoting the stability of platelet aggregates when released from platelet dense granules.

Application

Adenosine 5′-diphosphate has been used to study the release, neuronal effects, and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD⁺) in the rat brain. Adenosine 5′-diphosphate has also been used to compare prasugrel versus clopidogrel antiplatelet therapy after acute coronary syndrome.

Adenosine 5′-diphosphate monopotassium salt dihydrate (ADP) has been used:

• in titration to determine complex I-supported respiration in permeabilized muscle fibers
• in titrations to determine ADP-stimulated respiratory kinetics
• in the preparation of ADP solution for measuring mitochondrial respiration

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)