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A3293

Sigma-Aldrich

Anti-Human Albumin antibody produced in rabbit

whole antiserum

Synonyme(s) :

Albumin Antibody, Albumin Antibody - Anti-Human Albumin antibody produced in rabbit, Anti Human Albumin Antibody

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About This Item

Numéro MDL:
MFCD00162390
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

whole antiserum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Poids mol.

antigen 66.437-66.6 kDa

Contient

15 mM sodium azide

Espèces réactives

human

Technique(s)

indirect ELISA: 1:60,000
quantitative precipitin assay: 2.4-3.6

Numéro d'accès UniProt

P02768

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ALB(213)

Description générale

Albumin′s primary structure is composed of a single chain of amino acids and the secondary structure is composed of α-helix of six turns and 17 disulfide bridges. The tertiary structure is 3D and is composed of three domains I II and III. Each of these domains are made of sub-domains IAB, IC, IIAB, IIC, IIIAB, IIIC, respectively.

Spécificité

Anti-human albumin antibodies are specific for human albumin.

Immunogène

Human albumin

Application

Anti-Human Albumin antibody has been used in enzyme linked immunosorbent assay (ELISA) and in immobilization of antibodies for human serum albumin (HSA).
Anti-human albumin antibody may be used in quantitative precipitin assay, high-throughput protein microarray analysis and immunocytochemistry .
Rat hepatocytes were grown on collagen-coated coverslips, fixed in formalin and permeablized with methanol prior to incubation with rabbit anti-human albumin antibody.

Actions biochimiques/physiologiques

Albumin is a transport protein that binds a broad range of ligands such as fatty acids, bilirubin, hemin, drugs, amino acids and ions among several others . Albumin may also function as a zinc carrier protein and consequently regulate physiological processes .
Albumin plays a major role in transportation and deposition of many exogenous and endogenous substances in blood.

Forme physique

Supplied as a liquid containing 15mM sodium azide as preservative.

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Code de la classe de stockage

13 - Non Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

The analysis and characterisation of immuno-unreactive urinary albumin in healthy volunteers
Clavant S P, et al.
Clinical Biochemistry, 39(2), 143-151 (2006)
Interaction of bovine (BSA) and human (HSA) serum albumins with ionic surfactants: spectroscopy and modelling
Gelamo E L, et al.
Biochimica et Biophysica Acta, Protein Structure and Molecular Enzymology, 1594(1), 84-99 (2002)
Yi Luo et al.
The Journal of pharmacology and experimental therapeutics, 321(3), 884-891 (2007-03-21)
Epidermal growth factor (EGF) stimulation of cell cycle progression in cultured primary hepatocytes has previously been reported to be dependent on the mammalian target of rapamycin (mTOR) elements of the phosphoinositide 3-kinase (PI3K) signaling cascade and not the Akt pathway.
Real-time multianalyte biosensors based on interference-free multichannel monolithic quartz crystal microbalance
Jaruwongrungsee K, et al.
Biosensors And Bioelectronics, 67, 576-581 (2015)
Tien T Le et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 241(3), 493-504 (2012-01-26)
During vertebrate lens development, the lens placode in the embryonic ectoderm invaginates into a lens vesicle, which then separates from the surface epithelium, followed by two waves of fiber cell differentiation. In the mouse, multiple labs have shown that Jag1-Notch
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