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91C

Sigma-Aldrich

Leukocyte Naphthol AS-D Chloroacetate (Specific Esterase) Kit

Synonyme(s) :

Leder Stain

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About This Item

Code UNSPSC :
12352106
Nomenclature NACRES :
NA.47

Description

Kit formulated with all liquid reagents

Niveau de qualité

500

Durée de conservation

Expiry date on the label.

IVD

for in vitro diagnostic use

Application(s)

hematology
histology

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Application

Esterases are ubiquitous in nature and encompass a series of different enzymes acting upon select substrates. With the 91C kit, Naphthol AS-D Chloroacetate is enzymatically hydrolyzed by "specific esterase, " liberating a free naphthol compound. This then couples with a diazonium compound, forming highly colored deposits at sites of enzyme activity. This enzyme is usually considered specific for cells of granulocytic lineage. May be used to detect neutrophils in peripheral blood, bone marrow or tissue sections which have been paraffin embedded.

Composants de kit également disponibles séparément

Réf. du produit
Description
FDS
  • 915Citrate Solution, pH 3.6±0.1 (25 °C), 27 mM 50 mLFDS
  • 912Fast Red Violet LB Base Solution 10 mLFDS
  • 911Naphthol AS-D Chloroacetate Solution 10 mLFDS
  • 911Naphthol AS-D Chloroacetate Solution 50 mLFDS

Pictogrammes

Health hazardCorrosionExclamation mark
GHS08,GHS05,GHS07

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1 - Skin Sens. 1 - STOT RE 2 Oral - STOT SE 3

Organes cibles

Kidney, Respiratory system

Risques supp

EUH019

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Marvin Rüger et al.
Journal of neuroinflammation, 17(1), 325-325 (2020-10-31)
Bacterial meningitis is still a cause of severe neurological disability. The brain is protected from penetrating pathogens by the blood-brain barrier and the innate immune system. The invading pathogens are recognized by pattern recognition receptors including the G-protein-coupled formyl peptide
Paramahamsa Maturu et al.
Translational oncology, 7(4), 484-492 (2014-06-28)
The role of inflammation in cancer has been reported in various adult malignant neoplasms. By contrast, its role in pediatric tumors has not been as well studied. In this study, we have identified and characterized the infiltration of various inflammatory
Ralf A Linker et al.
Journal of immunology (Baltimore, Md. : 1950), 180(4), 2204-2213 (2008-02-06)
The neurotrophic cytokines ciliary neurotrophic factor and leukemia inhibitory factor (LIF) play a key role in neuronal and oligodendrocyte survival and as protective factors in neuroinflammation. To further elucidate the potential of endogenous LIF in modulating neuroinflammation, we studied myelin
Jung-Hwan Kim et al.
The Journal of allergy and clinical immunology, 137(2), 507-516 (2015-10-05)
The incidence of food allergies has increased dramatically during the last decade. Recently, probiotics have been studied for the prevention and treatment of allergic disease. We examined whether Bifidobacterium longum KACC 91563 and Enterococcus faecalis KACC 91532 have the capacity
Can Zhang et al.
Pesticide biochemistry and physiology, 171, 104727-104727 (2020-12-29)
Insecticide resistance is an ongoing challenge in agriculture and disease vector control. Here, we demonstrate a novel strategy to attenuate resistance. We used genomics tools to target fundamental energy-associated pathways and identified a potential "Achilles' heel" for resistance, a resistance-associated
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