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90878

Sigma-Aldrich

Poly(éthylène glycol)

BioUltra, 300

Synonyme(s) :

PEG

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About This Item

Formule linéaire :
H(OCH2CH2)nOH
Numéro CAS:
25322-68-3
Numéro MDL:
MFCD00081839
Code UNSPSC :
12352104
ID de substance PubChem :
24889419
Nomenclature NACRES :
NA.26

Gamme de produits

BioUltra

Forme

viscous liquid

Poids mol.

Mr 285-315

Impuretés

insoluble matter:, passes filter test
≤0.001% peroxides (as H2O2):

Indice de réfraction

n20/D 1.465

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

Solubilité

H2O: 50 mg/mL at 25 °C, clear, colorless

Densité

1.125 g/mL at 20 °C

Traces d'anions

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

Traces de cations

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

Absorption UV

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

Chaîne SMILES 

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clé InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Application


  • Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae.: This study explores the use of Poly(ethylene glycol) (PEG) in creating a lyophilized eukaryotic cell-free protein expression system. The research demonstrates how PEG facilitates the stabilization and preservation of cell-free systems, enhancing protein synthesis capabilities for various biochemical applications (Alfaro-Palma et al., 2024).

  • High-Contrast Luminescent Immunohistochemistry Using PEGylated Lanthanide Complexes.: The application of PEGylated lanthanide complexes in immunohistochemistry significantly improves the contrast and specificity of luminescent signals. This innovation aids in more accurate biochemical analysis and diagnostics (Su et al., 2022).

  • Analyzing Immune Response to Engineered Hydrogels by Hierarchical Clustering of Inflammatory Cell Subsets.: This research investigates the immune responses to PEG-based hydrogels used in tissue engineering. It provides insights into the biocompatibility and inflammatory reactions, essential for designing advanced biomaterials (Fernandez-Yague et al., 2022).

  • Person-Specific Biomolecular Coronas Modulate Nanoparticle Interactions with Immune Cells in Human Blood.: The study shows how PEGylation of nanoparticles affects their interaction with immune cells, influencing drug delivery systems and therapeutic efficacy in biochemistry and molecular biology (Ju et al., 2020).

  • A Post-Insertion Strategy for Surface Functionalization of Bacterial and Mammalian Cell-Derived Extracellular Vesicles.: This paper discusses the post-insertion method using PEG for surface functionalization of extracellular vesicles, enhancing their potential for targeted drug delivery and biochemical research (Jiang et al., 2021).

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

281.5 °F - closed cup

Point d'éclair (°C)

138.6 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
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Clinical cancer research : an official journal of the American Association for Cancer Research, 23(5), 1274-1285 (2017-02-25)
Vural Tagal et al.
Nature communications, 8, 14098-14098 (2017-01-20)
Mutations in the SMARCA4/BRG1 gene resulting in complete loss of its protein (BRG1) occur frequently in non-small cell lung cancer (NSCLC) cells. Currently, no single therapeutic agent has been identified as synthetically lethal with SMARCA4/BRG1 loss. We identify AURKA activity
Hongge Wang et al.
Oncogene, 39(14), 2905-2920 (2020-02-08)
PARP1 and PARP2 play critical roles in regulating DNA repair and PARP inhibitors have been approved for the treatment of BRCA1/2-mutated ovarian and breast cancers. It has long been known that PARP inhibition sensitizes cancer cells to DNA-damaging cytotoxic agents
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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