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88930

Sigma-Aldrich

Thionin acetate salt

for microscopy (Bact., Bot., Hist.)

Synonyme(s) :

3,7-Diamino-5-phenothiazinium acetate, Lauth’s violet

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About This Item

Formule empirique (notation de Hill):
C12H9N3S · C2H4O2
Numéro CAS:
78338-22-4
Poids moléculaire :
287.34
Numéro C.I. (Colour Index):
52000
Numéro Beilstein :
4345073
Numéro MDL:
MFCD00081194
Code UNSPSC :
12352200
ID de substance PubChem :
57653323
Nomenclature NACRES :
NA.25

Qualité

for microscopy (Bact., Bot., Hist.)

Forme

powder

Technique(s)

titration: suitable

Chaîne SMILES 

CC([O-])=O.Nc1ccc2nc3ccc(N)cc3[s+]c2c1

InChI

1S/C12H10N3S.C2H4O2/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;1-2(3)4/h1-6H,13-14H2;1H3,(H,3,4)/q+1;/p-1

Clé InChI

OWXBIRAFHWASMS-UHFFFAOYSA-M

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Application

Thionine (Lauth′s violet), a metachromatic dye, is widely used as a biological stain of materials such as DNA. Thionine is being studied as an electron mediator in the development of microbial fuel cells and electrochemical biosensors.

Code de la classe de stockage

13 - Non Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Ling Meng et al.
Biosensors & bioelectronics, 24(6), 1751-1756 (2008-10-24)
A glutamate biosensor based on the electrocatalytic oxidation of reduced nicotinamide adenine dinucleotide (NADH), which was generated by the enzymatic reaction, was developed via employing a single-walled carbon nanotubes/thionine (Th-SWNTs) nanocomposite as a mediator and an enzyme immobilization matrix. The
Liu Deng et al.
Analytical chemistry, 82(10), 4283-4287 (2010-04-21)
In this work we developed a fully integrated biofuel cell on a microchip, which consisted of glucose dehydrogenase supported (carbon nanotubes/thionine/gold nanoparticles)(8) multilayer as the anode, and the (carbon nanotubes/polylysine/laccase)(15) multilayer as the cathode. The as-obtained biofuel cell produced open
Jingman Han et al.
Biosensors & bioelectronics, 47, 243-247 (2013-04-16)
Here we report a one-step approach to synthesize graphene oxide-thionine-Au (GO-Thi-Au) nanocomposites using the synergistic effect of Thi and GO. Thi molecules adsorbed on the nanocomposites still kept the property of electroactive redox. Meanwhile, the resulting Au nanoparticles (AuNPs) of
Shujun Yu et al.
Biosensors & bioelectronics, 48, 224-229 (2013-05-22)
A highly sensitive label-free immunosensor for the detection of kanamycin had been developed using silver hybridized mesoporous ferroferric oxide nanoparticles (Ag@Fe₃O₄ NPs) and thionine mixed graphene sheet (TH-GS). TH was used as an electron transfer mediator. The electrical signal was
Wen Li et al.
Analytical chemistry, 84(17), 7583-7590 (2012-08-14)
Site-specific identification of DNA methylation and assay of MTase activity are important in determining specific cancer types, providing insights into the mechanism of gene repression, and developing novel drugs to treat methylation-related diseases. This work reports an electrochemical method for
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