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Principaux documents

52194

Sigma-Aldrich

Tetramethylrhodamine isothiocyanate–Dextran

average mol wt 500,000

Synonyme(s) :

TRITC Dextran, TRITC-Dextran 500, TRITC-Dextran

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About This Item

Numéro MDL:
MFCD00132418
Code UNSPSC :
12352116
Nomenclature NACRES :
NA.32

Source biologique

synthetic

Niveau de qualité

100

Forme

powder or crystals

Poids mol.

average mol wt 500,000

Ampleur du marquage

0.001-0.008 mol/mol TRITC glucose

Fluorescence

λex 550 nm; λem 575 nm±5 nm in 0.1 M Tris pH 8.0

Application(s)

cell analysis

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Catégories apparentées

Description générale

Tetramethylrhodamine isothiocyanate–Dextran, also known as TRITC-Dextran or TRITC-Dextran 500, is a fluorescent dye and a novel drug. The fluorescent activity of TRITC-Dextran is detected at 555nm wavelength. The TRITC-Dextran molecules are released in the cells through passive diffusion due to a concentration gradient.

Application

Tetramethylrhodamine isothiocyanate–Dextran (TRITC-Dextran 500) is use as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
BCCH0185
BCCF7837
BCCC8933
BCCB7967
BCBZ5532

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Thea van der Wijk et al.
The Journal of biological chemistry, 278(41), 40020-40025 (2003-07-23)
Osmotic swelling of Intestine 407 cells leads to an immediate increase in cell surface membrane area as determined using the fluorescent membrane dye FM 1-43. In addition, as measured by tetramethylrhodamine isothiocyanate (TRITC)-dextran uptake, a robust (>100-fold) increase in the
Margaret Clarke et al.
Journal of cell science, 115(Pt 14), 2893-2905 (2002-06-26)
The vacuolar H(+)-ATPase (V-ATPase) is a multi-subunit enzyme that plays important roles in eukaryotic cells. In Dictyostelium, it is found primarily in membranes of the contractile vacuole complex, where it energizes fluid accumulation by this osmoregulatory organelle and also in
Alexa Patzelt et al.
Journal of controlled release : official journal of the Controlled Release Society, 246, 174-182 (2016-09-20)
More and more investigations confirm that nanoparticles are incapable of overcoming the intact skin barrier in vivo. Do nanoparticles still have a future in dermal drug delivery? Unlike many other topically applied substances, nanoparticles have not been reported to utilize
Matthias Osswald et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 22(24), 6078-6087 (2016-08-16)
The role of blood-brain barrier (BBB) integrity for brain tumor biology and therapy is a matter of debate. We developed a new experimental approach using in vivo two-photon imaging of mouse brain metastases originating from a melanoma cell line to
Celine Mateo et al.
Neuron, 96(4), 936-948 (2017-11-07)
Resting-state signals in blood-oxygenation-level-dependent (BOLD) imaging are used to parcellate brain regions and define "functional connections" between regions. Yet a physiological link between fluctuations in blood oxygenation with those in neuronal signaling pathways is missing. We present evidence from studies
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Articles

FITC-labelled polysaccharides

Additional information about FITC-labelled polysaccarides including FITC-Dextran, FITC-DEAE-dextran (FDD), FITC-carboxymethyl-dextran (FCM-Dextran). This page discusses the impact of weight-average molecular weight on the respective molecule dimensions and other physical properties

FITC-labelled polysaccharides

Additional information about FITC-labelled polysaccarides including FITC-Dextran, FITC-DEAE-dextran (FDD), FITC-carboxymethyl-dextran (FCM-Dextran). This page discusses the impact of weight-average molecular weight on the respective molecule dimensions and other physical properties

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