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311383

Sigma-Aldrich

Arsenic(III) oxide

ACS reagent (primary standard)

Synonyme(s) :

Arsenic trioxide, Arsenous acid

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About This Item

Formule empirique (notation de Hill):
As2O3
Numéro CAS:
1327-53-3
Poids moléculaire :
197.84
Numéro CE :
215-481-4
Numéro MDL:
MFCD00003433
Code UNSPSC :
12171602
ID de substance PubChem :
329753664
Nomenclature NACRES :
NB.24

Qualité

ACS reagent (primary standard)

Niveau de qualité

200

Pression de vapeur

0 hPa ( 66 °C)

Pureté

99.95-100.05%

Forme

powder

Pertinence de la réaction

reagent type: catalyst
core: arsenic

Résidus de calcination

≤0.02%

Solubilité

dilute HCl: insoluble ≤0.01%

Traces d'anions

S2-: passes test (lim. ~0.001%)
chloride (Cl-): ≤0.005%

Traces de cations

Fe: ≤5 ppm
Pb: ≤0.002%
Sb: ≤0.05%

Chaîne SMILES 

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

Clé InChI

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Arsenic (III) oxide, also referred to as arsenic trioxide, is an amphoteric oxide that is used as a raw material to produce several arsenic-based compounds.

Application

Arsenic (III) oxide is used
  • In the synthesis of arsenic pentafluoride (AsF5) by static fluorination method in a closed system.
  • In the preparation of arsenic-doped ZnO films by adding As2O3 to zinc acetate, 2-methoxyethanol, and monoethanolamine by sol-gel spin coating method.

Mention d'avertissement

Danger

Mentions de danger

H300,H314,H350,H372,H410

Classification des risques

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

Organes cibles

Respiratory system,Cardio-vascular system,Gastrointestinal tract

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Yanfei Jia et al.
PloS one, 8(1), e54774-e54774 (2013-02-06)
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and has
Liangchun Hao et al.
Journal of pediatric hematology/oncology, 35(2), e67-e70 (2013-02-16)
The aim of this study was to investigate the hepatotoxicity induced by arsenic trioxide (As2O3) at a therapeutic dose for pediatric acute promyelocytic leukemia (APL). A total of APL patients received As2O3 treatment by IV drip. Hepatotoxicity was monitored based
Yuhua Fan et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 31(1), 80-91 (2013-02-01)
Arsenic trioxide (As2O3) is a highly effective agent for treatment of acute promyelocytic leukemia (APL). However, consecutively administered As2O3 induces serious adverse cardiac effects, including long QT syndrome (LQTs) and even sudden cardiac death. Previous studies have shown that genistein
Huihui Wang et al.
Environmental toxicology, 28(5), 267-275 (2013-04-17)
Although arsenic is effective in the treatment of acute promyelocytic leukemia (APL), as a well-known environmental toxicant, the side effects of arsenic treatment and arsenic methylation metabolism of the patients are rarely reported. In this manuscript, we investigated 23 APL
Athena Kritharis et al.
Annals of hematology, 92(6), 719-730 (2013-03-16)
For more than 2,000 years, arsenic and its derivatives have shown medical utility. Owing to the toxicities and potential carcinogenicity of arsenicals, their popularity has fluctuated. The exact mechanism of action of therapeutic arsenic is not well characterized but likely
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