SMB00953

2-Cyano-3,3-diphenylacrylic acid

≥95%

• Synonyme(s) : α-Cyano-β-diphenylacrylic acid, 2-Cyano-3,3-diphenylpropenoic acid
• Formule empirique (notation de Hill): C₁₆H₁₁NO₂
• Numéro CAS: 10380-41-3
• Poids moléculaire : 249.26
• Code UNSPSC : 12352106
• Nomenclature NACRES : NA.22

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 200
• Pureté: ≥95%
• Forme: solid
• Poids mol.: 249.26 g/mol
• Conditions de stockage: (Tightly closed. Dry.)
• Technique(s): HPLC: suitable
• Couleur: white to off-white
• Température de stockage: 2-8°C
• InChI: 1S/C16H11NO2/c17-11-14(16(18)19)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H,(H,18,19)
• Clé InChI: VSXIZXFGQGKZQG-UHFFFAOYSA-N

Description

Description générale

2-Cyano-3,3-diphenylacrylic acid (CDA) belongs to the class of α,β-unsaturated carboxylic acids. It is a primary metabolite of Octocrylene, an organic sunscreen that functions by absorbing UVB radiation and short UVA wavelengths, commonly utilized in cosmetics for sun protection. CDA exhibits prolonged systemic availability after dermal exposure which may accumulate in the body. It can be used to study skin-permeable selective cyclooxygenaswe-2 inhibitor composition, and to study hydrophilic components of cosmetic compositions, such as in sunscreen.

Application

2-Cyano-.3-diphenylacrylic acid finds application in metabolomics, cosmetics and cancer research

Actions biochimiques/physiologiques

Within the human body, Octocrylene, a non-polar compound, undergoes metabolism to become a water-soluble metabolite 2-cyano-3,3-diphenylacrylic acid, which is excreted through the kidneys. A pilot study in the general population has consistently detected CDAA, and its levels have been linked to recent sunscreen application.

Caractéristiques et avantages

• High quality compound suitable for multiple research applications
• Compatible with a wide variety of chromatographic and spectrometry techniques

Autres remarques

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This product is intended for research purposes only, and it is not meant for human consumption.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable