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Key Documents

PHR1085

Supelco

Homosalate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

3,3,5-Trimethylcyclohexyl salicylate, 2-Hydroxybenzoic acid 3,3,5-trimethylcyclohexyl ester, Homomenthyl salicylate, Homosalate

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About This Item

Formule empirique (notation de Hill):
C16H22O3
Numéro CAS:
Poids moléculaire :
262.34
Numéro Beilstein :
2731604
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to USP 1311408

Famille d'API

homosalate

CofA (certificat d'analyse)

current certificate can be downloaded

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care
pharmaceutical (small molecule)

Format

neat

Température de stockage

2-30°C

Chaîne SMILES 

CC1CC(CC(C)(C)C1)OC(=O)c2ccccc2O

InChI

1S/C16H22O3/c1-11-8-12(10-16(2,3)9-11)19-15(18)13-6-4-5-7-14(13)17/h4-7,11-12,17H,8-10H2,1-3H3

Clé InChI

WSSJONWNBBTCMG-UHFFFAOYSA-N

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Description générale

Homosalate is a UV filter that protects the skin from the harmful effects of UVB (280-315 nm) and UVA II (315-340 nm) radiations. It is widely utilized in make-up, sunscreen and topical formulations.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Homosalate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography methods.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAC3174 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

339.4 °F - closed cup

Point d'éclair (°C)

170.8 °C - closed cup


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Lot/Batch Number

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Consulter la Bibliothèque de documents

Rapid analysis of ultraviolet filters using dispersive liquid-liquid microextraction coupled to headspace gas chromatography and mass spectrometry
Pierson SA, et al.
Journal of Separation Science, 41(15), 3081-3088 (2018)
Homosalate
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 37(2), 2163-2163 (2013)
Supercritical fluid extraction and high performance liquid chromatography determination of homosalate in lipsticks
Salvador A, et al.
Chromatographia, 54(11-12), 795-797 (2001)
Benjamin Choquenet et al.
Journal of natural products, 71(6), 1117-1118 (2008-06-03)
Given that flavonoids are known for their ultraviolet (UV)B photoprotective properties in plants that contain them, we chose to study quercetin (1) and rutin (2) as agents that could potentially be used in sunscreen products. These two substances proved to
Yufeng Zhang et al.
Journal of chromatography. A, 1271(1), 56-61 (2012-12-15)
In the present study, a rapid, highly efficient and environmentally friendly sample preparation method named temperature-controlled ionic liquid dispersive liquid-phase microextraction (TC-IL-DLPME), followed by high performance liquid chromatography (HPLC) was developed for the extraction, preconcentration and determination of four benzophenone-type

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