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B5899

Supelco

Buflomedil hydrochloride

analytical standard

Synonyme(s) :

4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone

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About This Item

Formule empirique (notation de Hill):
C17H25NO4 · HCl
Numéro CAS:
35543-24-9
Poids moléculaire :
343.85
Numéro CE :
252-611-9
Numéro MDL:
MFCD00078965
Code UNSPSC :
41116107
ID de substance PubChem :
329773268
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

200

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

Chaîne SMILES 

Cl.COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1

InChI

1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H

Clé InChI

ZDPACSAHMZADFZ-UHFFFAOYSA-N

Informations sur le gène

human ... EBP(10682)

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Description générale

Buflomedil hydrochloride is a vasoactive agent. Its mode of action involves increasing the peripheral and cerebral blood flow in ischaemic tissues of patients, who are mostly affected with vascular diseases.

Application

Buflomedil hydrochloride may be used as an analytical standard for the determination of buflomedil in biological matrices using high-performance liquid chromatography technique. It may also be used as an analytical reference standard for the quantification of the analyte in pharmaceutical formulations and serum samples using electroanalytical and chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number

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F Mallard et al.
Chirurgie de la main, 31(6), 358-363 (2012-11-28)
Digital tourniquet is a quick, simple and reliable method to ensure a bloodless operative field distal to the MP joint. However, a forgotten tourniquet is an exceptional but serious complication related to digital ischemia. Few cases were reported in literature
Cutaneous granulomatous reaction from mesotherapy.
Gonca Gokdemir et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 35(2), 291-293 (2009-02-14)
D Tsantilas et al.
International angiology : a journal of the International Union of Angiology, 28(3), 170-174 (2009-01-29)
Our understanding of vascular pathophysiology has significantly improved during the past two decades. Patients with type 2 diabetes mellitus have an increased vascular risk and a series of modifiable risk factors play a crucial role in the atherosclerotic process. The
Wei Wang et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 47(7), 934-940 (2012-09-21)
The microbial transformation of buflomedil by Cunninghamella blakesleana AS 3.153 was studied, as well as a microbial model which can be used to mimic metabolism of buflomedil in mammal was established. Experiments were conducted to screen the capabilities of four
Denise Salles Coelho da Mota et al.
Clinics (Sao Paulo, Brazil), 64(8), 797-802 (2009-08-20)
This study investigated the effects of buflomedil and pentoxifylline, both of which are used in reconstructive surgery of hamster skin flap microcirculation, and evaluated the skin flap survival rate by orthogonal polarization spectral imaging. Twenty-four adult male Syrian golden hamsters
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