A8251

Acriflavine hydrochloride

Powder

• Synonyme(s) : 3,6-Diamino-10-methylacridinium chloride hydrochloride, Euflavine
• Numéro CAS: 8063-24-9
• Numéro Beilstein : 6265525
• Numéro MDL: MFCD00069039
• Code UNSPSC : 12171500
• ID de substance PubChem : 24891216
• Nomenclature NACRES : NA.47

Propriétés

• product name: Acriflavine hydrochloride, fluorescent dye
• Niveau de qualité: 200
• Forme: powder
• Composition: Acriflavine HCL content, 10-50% ; Proflavine HCL, 25-70%
• Couleur: faint brown to brown, and Orange to Dark Orange and Red to Very Dark Red
• Pf: 260 °C (dec.) (lit.)
• Solubilité: H₂O: 1 mg/mL
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: [Cl-].Cl[H].Cl[H].Nc1ccc2cc3ccc(N)cc3nc2c1.C[n+]4c5cc(N)ccc5cc6ccc(N)cc46
• InChI: 1S/C14H13N3.C13H11N3.3ClH/c1-17-13-7-11(15)4-2-9(13)6-10-3-5-12(16)8-14(10)17;14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;;;/h2-8H,1H3,(H3,15,16);1-7H,14-15H2;3*1H
• Clé InChI: MKLTXAHQKDVBLY-UHFFFAOYSA-N

Description

Application

In living mice, acriflavine hydrochloride has been used in the confocal laser endomicroscopy to check the crypt structure in mucosa. It has also been used in Neurospora strain selection by checking the acriflavine resistance.

Actions biochimiques/physiologiques

Acriflavine hydrochloride is a fluorescent dye. It is used as a topical contrast agent. It mainly stains nuclei and is applied to tissues before microscopy.

Autres remarques

A mixture of 3,6-diamino-10-methylacridinium (acriflavin) and 3,6-diaminoacridine (proflavin)

Informations sur la sécurité

• Pictogrammes: GHS05,GHS07,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H302,H318,H411
• Conseils de prudence: P264 - P273 - P280 - P301 + P312 - P305 + P351 + P338 - P391
• Classification des risques: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves